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Volume 28, Number 12—December 2022
Research

Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France

Nadim CassirComments to Author , Florian Cardona, Hervé Tissot-Dupont, Christiane Bruel, Barbara Doudier, Salima Lahouel, Karim Bendamardji, Céline Boschi, Sarah Aherfi, Sophie Edouard, Jean-Christophe Lagier, Philippe Colson, Philippe Gautret, Pierre-Edouard Fournier, Philippe Parola, Philippe Brouqui, Bernard La-Scola, and Matthieu Million
Author affiliations: IHU-Méditerranée Infection, Marseille, France (N. Cassir, F. Cardona, H. Tissot-Dupont, B. Doudier, S. Lahouel, K. Bendamardji, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P.-E. Fournier, P. Parola, P. Brouqui, B. La-Scola, M. Million); Aix-Marseille Université, IRD, AP-HM, MEPHI, Marseille (N. Cassir, H. Tissot-Dupont, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P. Brouqui, B. La-Scola, M. Million); Assistance Publique Hôpitaux de Marseille, Marseille (F. Cardona, B. Doudier, S. Lahouel, K. Bendamardji); Regional Health Agency of Provence-Alpes-Côte d'Azur (ARS Paca), Marseille (C. Bruel); Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille (P.-E. Fournier, P. Parola)

Main Article

Figure 1

Sites of monkeypox lesions in observational cohort study of evolving epidemiologic, clinical, and virological features of monkeypox in southern France, 2022. A) Primary inoculation site showing an irregular pustule with necrotic crust of the right nipple. B) Pustular lesions with a crusted center on the mucosa of the upper lip, close to the left oral commissure and left nasal orifice. C) Pustules circumferentially distributed on the anal margin and perianal skin of varying sizes and stages of evolution; some with central necrotic crusts. D) Perineally extended purpuric lesions. E) Scrotal lesions of varying sizes and stages of evolution with edema surrounding the larger ulcero-hemorrhagic ulcers. F) Scattered papules, pustules, and umbilicated pustules surrounded by an erythematous halo on the back. G) Reddened and swollen right palatine tonsil with a fibrin-covered ulcer. H) Pustular lesion of the nose with a necrotic central crust, whitish deposit, and erythematous halo.

Figure 1. Sites of monkeypox lesions in observational cohort study of evolving epidemiologic, clinical, and virological features of monkeypox in southern France, 2022. A) Primary inoculation site showing an irregular pustule with necrotic crust of the right nipple. B) Pustular lesions with a crusted center on the mucosa of the upper lip, close to the left oral commissure and left nasal orifice. C) Pustules circumferentially distributed on the anal margin and perianal skin of varying sizes and stages of evolution; some with central necrotic crusts. D) Perineally extended purpuric lesions. E) Scrotal lesions of varying sizes and stages of evolution with edema surrounding the larger ulcero-hemorrhagic ulcers. F) Scattered papules, pustules, and umbilicated pustules surrounded by an erythematous halo on the back. G) Reddened and swollen right palatine tonsil with a fibrin-covered ulcer. H) Pustular lesion of the nose with a necrotic central crust, whitish deposit, and erythematous halo.

Main Article

Page created: October 04, 2022
Page updated: November 21, 2022
Page reviewed: November 21, 2022
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