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Volume 28, Number 12—December 2022

Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France

Nadim CassirComments to Author , Florian Cardona, Hervé Tissot-Dupont, Christiane Bruel, Barbara Doudier, Salima Lahouel, Karim Bendamardji, Céline Boschi, Sarah Aherfi, Sophie Edouard, Jean-Christophe Lagier, Philippe Colson, Philippe Gautret, Pierre-Edouard Fournier, Philippe Parola, Philippe Brouqui, Bernard La-Scola, and Matthieu Million
Author affiliations: IHU-Méditerranée Infection, Marseille, France (N. Cassir, F. Cardona, H. Tissot-Dupont, B. Doudier, S. Lahouel, K. Bendamardji, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P.-E. Fournier, P. Parola, P. Brouqui, B. La-Scola, M. Million); Aix-Marseille Université, IRD, AP-HM, MEPHI, Marseille (N. Cassir, H. Tissot-Dupont, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P. Brouqui, B. La-Scola, M. Million); Assistance Publique Hôpitaux de Marseille, Marseille (F. Cardona, B. Doudier, S. Lahouel, K. Bendamardji); Regional Health Agency of Provence-Alpes-Côte d'Azur (ARS Paca), Marseille (C. Bruel); Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille (P.-E. Fournier, P. Parola)

Main Article

Table 1

Demographic and epidemiologic characteristics of patients with monkeypox in Marseille during the 2022 outbreak in southern France*

Variable No. patients†
Age, y, median (IQR)
36 (30–42)
F 3 (2.2)
133 (97.8)
Sexual orientation
Men who have sex with men 125 (91.9)
Using PrEP 30 (24)
Heterosexual men 2 (1.5)
Heterosexual women
3 (2.2)
History of smallpox vaccination
Childhood vaccine 7 (5.1)
Postexposure vaccine 6 (4.4)
Preexposure vaccine
2 (1.5)
Total 21 (15.4)
<500 CD4/mm3 5 (23.8)
<200 CD4/mm3
Possible exposure to monkeypox
Sexual partner with monkeypox 21 (15.4)
New sexual partners‡ 115 (84.6)
Attendance at a Pride event 7 (5.2)
Recent travel to an endemic country 0
Recent travel to an epidemic country 17 (12.5)

*Values are no. (%) patients except as indicated. PrEP, preexposure prophylaxis; CD4, CD4 T lymphocyte. †Total number of patients in the study was 136. ‡Single or multiple new sexual partners in the previous 21 d.

Main Article

Page created: October 04, 2022
Page updated: November 21, 2022
Page reviewed: November 21, 2022
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