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Volume 28, Number 12—December 2022
Research

Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France

Nadim CassirComments to Author , Florian Cardona, Hervé Tissot-Dupont, Christiane Bruel, Barbara Doudier, Salima Lahouel, Karim Bendamardji, Céline Boschi, Sarah Aherfi, Sophie Edouard, Jean-Christophe Lagier, Philippe Colson, Philippe Gautret, Pierre-Edouard Fournier, Philippe Parola, Philippe Brouqui, Bernard La-Scola, and Matthieu Million
Author affiliations: IHU-Méditerranée Infection, Marseille, France (N. Cassir, F. Cardona, H. Tissot-Dupont, B. Doudier, S. Lahouel, K. Bendamardji, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P.-E. Fournier, P. Parola, P. Brouqui, B. La-Scola, M. Million); Aix-Marseille Université, IRD, AP-HM, MEPHI, Marseille (N. Cassir, H. Tissot-Dupont, C. Boschi, S. Aherfi, S. Edouard, J.-C. Lagier, P. Colson, P. Gautret, P. Brouqui, B. La-Scola, M. Million); Assistance Publique Hôpitaux de Marseille, Marseille (F. Cardona, B. Doudier, S. Lahouel, K. Bendamardji); Regional Health Agency of Provence-Alpes-Côte d'Azur (ARS Paca), Marseille (C. Bruel); Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille (P.-E. Fournier, P. Parola)

Main Article

Table 2

Clinical characteristics of symptomatic patients with monkeypox in Marseille during the 2022 outbreak in southern France*

Variable No. (%) patients
Systemic features
>1 systemic feature 98 (73)
Systemic symptoms before rash onset 90 (69.8)
Fever 72 (55.8)
Influenza-like illness 44 (35.1)
Sore throat
 11 (8.5)
Clinical features of rash
Approximate number of lesions
>50 0
11–50 17 (13.2)
1–10 98 (73)
Type of lesion
Papular 26 (21)
Vesicular 60 (49)
Pustular 25 (20)
Scabbed 10 (7.8)
Asynchronous rash
 41 (30.1)
Lesion location
Genital 68 (52.7)
Perianal 63 (48.8)
Oral ulcer 3 (2.3)
Perioral 22 (17.1)
Hands and feet 13 (10.1)
Trunk
 28 (21.7)
Lymphadenopathy
Any lymphadenopathy 51 (39.5)
Regional at site of lesion 47 (36.4)
Cervical 26 (20.2)
Inguinal 28 (21.7)
Generalized
 4 (3.1)
Complications
Any complication 34 (26.4)
Complication by type
Proctitis 30 (23.3)
Tonsillitis 5 (3.9)
Penile edema 5 (3.9)
Bacterial skin abscess 4 (3.1%)
Exanthem 3 (2.3%)

*Total number of patients evaluated was 129.

Main Article

Page created: October 04, 2022
Page updated: November 21, 2022
Page reviewed: November 21, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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