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Volume 28, Number 3—March 2022

Relationship of SARS-CoV-2 Antigen and Reverse Transcription PCR Positivity for Viral Cultures

Dustin W. CurrieComments to Author , Melisa M. Shah, Phillip P. Salvatore, Laura Ford, Melissa J. Whaley, Jennifer Meece, Lynn Ivacic, Natalie J. Thornburg, Azaibi Tamin, Jennifer L. Harcourt, Jennifer Folster, Magdalena Medrzycki, Shilpi Jain, Phili Wong, Kimberly Goffard, Douglas Gieryn, Juliana Kahrs, Kimberly Langolf, Tara Zochert, Christopher H. Hsu, Hannah L. Kirking, Jacqueline E. Tate, and for the CDC COVID-19 Response Epidemiology Field Studies Team1
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D.W. Currie, M.M. Shah, P.P. Salvatore, L. Ford, M.J. Whaley, N.J. Thornburg, A. Tamin, J.L. Harcourt, J. Folster, M. Medrzycki, S. Jain, P. Wong, C.H. Hsu, H.L. Kirking, J.E. Tate); Marshfield Clinic Research Institute, Marshfield, Wisconsin, USA (J. Meece, L. Ivacic); Winnebago County Health Department, Oshkosh, Wisconsin, USA (K. Goffard, D. Gieryn); University of Wisconsin‒Oshkosh, Oshkosh (J. Kahrs, K. Langolf, T. Zochert)

Main Article

Table 1

Positive predictive value of the BinaxNOW COVID-19 Antigen Card Test and RT-PCR relative to viral culture, Winnebago County, Wisconsin, USA, November‒December 2020*

SARS-CoV-2 diagnostic test result No. culture positive No. culture negative Total Positive predictive value, %
BinaxNOW positive 191 78 269 71.0
RT-PCR positive 200 134 334 59.9

*BinaxNOW, RT-PCR, reverse transcription PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Main Article

1Members of CDC COVID-19 Response Epidemiology Field Studies Team who collected data are listed at the end of this article.

Page created: November 12, 2021
Page updated: February 21, 2022
Page reviewed: February 21, 2022
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