TY - JOUR AU - Laing, Eric AU - Weiss, Carol AU - Samuels, Emily AU - Coggins, Si’Ana AU - Wang, Wei AU - Wang, Richard AU - Vassell, Russell AU - Sterling, Spencer AU - Tso, Marana AU - Conner, Tonia AU - Goguet, Emilie AU - Moser, Matthew AU - Jackson-Thompson, Belinda AU - Illinik, Luca AU - Davies, Julian AU - Ortega, Orlando AU - Parmelee, Edward AU - Hollis-Perry, Monique AU - Maiolatesi, Santina AU - Wang, Gregory AU - Ramsey, Kathleen AU - Reyes, Anatalio AU - Alcorta, Yolanda AU - Wong, Mimi AU - Lindrose, Alyssa AU - Duplessis, Christopher AU - Tribble, David AU - Malloy, Allison M.W. AU - Burgess, Timothy AU - Pollett, Simon AU - Olsen, Cara AU - Broder, Christopher AU - Mitre, Edward T1 - Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers T2 - Emerging Infectious Disease journal PY - 2022 VL - 28 IS - 4 SP - 828 SN - 1080-6059 AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies. KW - COVID-19 KW - coronavirus disease KW - SARS-CoV-2 KW - severe acute respiratory syndrome coronavirus 2 KW - viruses KW - respiratory infections KW - zoonoses KW - vaccine-preventable diseases KW - BNT162b2 KW - healthcare workers KW - United States DO - 10.3201/eid2804.212037 UR - https://wwwnc.cdc.gov/eid/article/28/4/21-2037_article ER - End of Reference