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Volume 28, Number 4—April 2022
Research

Genomic Epidemiology of Early SARS-CoV-2 Transmission Dynamics, Gujarat, India

Jayna RaghwaniComments to Author , Louis du Plessis, John T. McCrone, Sarah C. Hill, Kris V. Parag, Julien Thézé, Dinesh Kumar, Apurva Puvar, Ramesh Pandit, Oliver G. Pybus, Guillaume Fournié, Madhvi Joshi1, and Chaitanya Joshi1
Author affiliations: University of Oxford, Oxford, UK (J. Raghwani, L. du Plessis, O.G. Pybus); University of Edinburgh, Edinburgh, Scotland, UK (J.T. McCrone); Royal Veterinary College, Hatfield, UK (S.C. Hill, O.G. Pybus, G. Fournié); University of Bristol, Bristol, UK (K.V. Parag), Université Clermont-Auvergne, Saint-Genès-Champanelle, France (J. Thézé),; Gujarat Biotechnology Research Centre, Gandhinagar, India (D. Kumar, A. Puvar, R. Pandit, M. Joshi, C. Joshi)

Main Article

Figure 2

Size, duration, and importation of severe acute respiratory syndrome coronavirus 2 transmission lineages, Gujarat, India. A) Tree map summarizing the 113 detected transmission lineages by size. Colors indicate the duration of persistence of the lineage, and areas indicate the size of the transmission lineages. Lineage duration corresponds to time between the lineage’s oldest and most recently sampled genomes. B) Strong log‒linear relationship between size and mean tMRCA of each transmission lineages. Gray shading indicates time of testing; dashed line indicates slope. C) Breakdown of virus importations into Gujarat from other states in India or other countries. The number of location state transitions were estimated by using a robust counting approach (21) and a 3-location discrete trait phylogeographic analysis. tMRCA, time to most recent common ancestor.

Figure 2. Size, duration, and importation of severe acute respiratory syndrome coronavirus 2 transmission lineages, Gujarat, India. A) Tree map summarizing the 113 detected transmission lineages by size. Colors indicate the duration of persistence of the lineage, and areas indicate the size of the transmission lineages. Lineage duration corresponds to time between the lineage’s oldest and most recently sampled genomes. B) Strong log‒linear relationship between size and mean tMRCA of each transmission lineages. Gray shading indicates time of testing; dashed line indicates slope. C) Breakdown of virus importations into Gujarat from other states in India or other countries. The number of location state transitions were estimated by using a robust counting approach (21) and a 3-location discrete trait phylogeographic analysis. tMRCA, time to most recent common ancestor.

Main Article

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Main Article

1These senior authors contributed equally to this article.

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