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Volume 28, Number 4—April 2022
Dispatch

SARS-CoV-2 Outbreak among Malayan Tigers and Humans, Tennessee, USA, 2020

Heather N. GromeComments to Author , Becky Meyer, Erin Read, Martha Buchanan, Andrew Cushing, Kaitlin Sawatzki, Kara J. Levinson, Linda S. Thomas, Zachary Perry, Anna Uehara, Ying Tao, Krista Queen, Suxiang Tong, Ria Ghai, Mary-Margaret Fill, Timothy F. Jones, William Schaffner, and John Dunn
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (H.N. Grome, A. Uehara, Y. Tao, K. Queen, S. Tong, R. Ghai); Tennessee Department of Health, Nashville, Tennessee, USA (H.N. Grome, M.-M. Fill, T.F. Jones, J. Dunn); Knox County Health Department, Knoxville, Tennessee (B. Meyer, E. Read, M. Buchanan); University of Tennessee College of Veterinary Medicine, Knoxville (A. Cushing); Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts, USA (K. Sawatzki); Tennessee Laboratory Services, Nashville (K.J. Levinson, L.S. Thomas, Z. Perry); Vanderbilt University School of Medicine, Nashville (W. Schaffner)

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Figure 1

Timeline of events identified during the epidemiologic investigation of an outbreak of SARS-CoV-2 infection among Malayan tigers and humans at a zoo, Tennessee, USA, October 12–30, 2020. Dates related to tiger events are shown above the timeline; dates related to human events are shown below the timeline. Ct values for the first positive open reading frame 1b reverse transcription PCR test per animal are shown; methods for extraction and Ct value calculation were described previously by Sawatzki et al. (11). Ct, cycle threshold; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Figure 1. Timeline of events identified during the epidemiologic investigation of an outbreak of SARS-CoV-2 infection among Malayan tigers and humans at a zoo, Tennessee, USA, October 12–30, 2020. Dates related to tiger events are shown above the timeline; dates related to human events are shown below the timeline. Ct values for the first positive open reading frame 1b reverse transcription PCR test per animal are shown; methods for extraction and Ct value calculation were described previously by Sawatzki et al. (11). Ct, cycle threshold; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

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References
  1. Bosco-Lauth  AM, Hartwig  AE, Porter  SM, Gordy  PW, Nehring  M, Byas  AD, et al. Experimental infection of domestic dogs and cats with SARS-CoV-2: Pathogenesis, transmission, and response to reexposure in cats. Proc Natl Acad Sci U S A. 2020;117:263828. DOIPubMedGoogle Scholar
  2. Bao  L, Song  Z, Xue  J, Gao  H, Liu  J, Wang  J, et al. Susceptibility and attenuated transmissibility of SARS-CoV-2 in domestic cats. J Infect Dis. 2021;223:131321. DOIPubMedGoogle Scholar
  3. McAloose  D, Laverack  M, Wang  L, Killian  ML, Caserta  LC, Yuan  F, et al. From people to Panthera: natural SARS-CoV-2 infection in tigers and lions at the Bronx Zoo. MBio. 2020;11:e0222020. DOIPubMedGoogle Scholar
  4. Shi  J, Wen  Z, Zhong  G, Yang  H, Wang  C, Huang  B, et al. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science. 2020;368:101620. DOIPubMedGoogle Scholar
  5. Halfmann  PJ, Hatta  M, Chiba  S, Maemura  T, Fan  S, Takeda  M, et al. Transmission of SARS-CoV-2 in domestic cats. N Engl J Med. 2020;383:5924. DOIPubMedGoogle Scholar
  6. Barrs  VR, Peiris  M, Tam  KWS, Law  PYT, Brackman  CJ, To  EMW, et al. SARS-CoV-2 in quarantined domestic cats from COVID-19 households or close contacts, Hong Kong, China. Emerg Infect Dis. 2020;26:30714. DOIPubMedGoogle Scholar
  7. Cushing  AC, Sawatzki  K, Grome  HN, Puryear  WB, Kelly  N, Runstadler  J. DURATION OF ANTIGEN SHEDDING AND DEVELOPMENT OF ANTIBODY TITERS IN MALAYAN TIGERS (PANTHERA TIGRIS JACKSONI) NATURALLY INFECTED WITH SARS-CoV-2. J Zoo Wildl Med. 2021;52:12248. DOIPubMedGoogle Scholar
  8. Centers for Disease Control and Prevention. Case investigation & contact tracing guidance 2021 [cited 2021 September 30]. https://www.cdc.gov/coronavirus/2019-ncov/php/contact-tracing/contact-tracing-plan/appendix.html
  9. Cai  J, Sun  W, Huang  J, Gamber  M, Wu  J, He  G. Indirect virus transmission in cluster of COVID-19 cases, Wenzhou, China. Emerg Infect Dis. 2020;26:13435. DOIPubMedGoogle Scholar
  10. Jang  S, Han  SH, Rhee  JY. Cluster of coronavirus disease associated with fitness dance classes, South Korea. Emerg Infect Dis. 2020;26:191720. DOIPubMedGoogle Scholar
  11. Sawatzki  K, Hill  NJ, Puryear  WB, Foss  AD, Stone  JJ, Runstadler  JA. Host barriers to SARS-CoV-2 demonstrated by ferrets in a high-exposure domestic setting. Proc Natl Acad Sci U S A. 2021;118:e2025601118. DOIPubMedGoogle Scholar
  12. Paden  CR, Tao  Y, Queen  K, Zhang  J, Li  Y, Uehara  A, et al. Rapid, sensitive, full-genome sequencing of severe acute respiratory syndrome coronavirus 2. Emerg Infect Dis. 2020;26:24015. DOIPubMedGoogle Scholar
  13. Sagulenko  P, Puller  V, Neher  RA. TreeTime: Maximum-likelihood phylodynamic analysis. Virus Evol. 2018;4:vex042. DOIPubMedGoogle Scholar
  14. Hadfield  J, Megill  C, Bell  SM, Huddleston  J, Potter  B, Callender  C, et al. Nextstrain: real-time tracking of pathogen evolution. Bioinformatics. 2018;34:41213. DOIPubMedGoogle Scholar

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Page updated: March 19, 2022
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