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Volume 28, Number 8—August 2022
Research

Characterization of Emerging Serotype 19A Pneumococcal Strains in Invasive Disease and Carriage, Belgium

Stefanie DesmetComments to Author , Heidi Theeten, Lies Laenen, Lize Cuypers, Piet Maes, Wouter Bossuyt, Liesbet Van Heirstraeten, Willy E. Peetermans, and Katrien Lagrou
Author affiliations: University Hospitals Leuven, Leuven, Belgium (S. Desmet, L. Laenen, L. Cuypers, W. Bossuyt, W.E. Peetermans, K. Lagrou); Katholieke Universiteit Leuven, Leuven (S. Desmet, P. Maes, W. Bossuyt, W.E. Peetermans, K. Lagrou); University of Antwerp, Antwerp, Belgium (H. Theeten, L. Van Heirstraeten); Katholieke Universiteit Leuven‒University Hospitals Leuven, Leuven (W. Bossuyt)

Main Article

Table 2

Characteristics of serotype 19A pneumococcal sequence types after the PCV13 to PCV10 switch, Belgium*

GPSC ST No. IPD in person <2 years of age IPD in person >65 years of age Carriage in children <3 years of age Pilus 1 No pilus Penicillin resistant Most frequent PBP profile Erythromycin resistant Resistance gene Tetracycline resistant Resistance gene
GPSC4
ST416 79 26 26 27 76 3 0 0-0-0 (74); new-0-0 (3); 1-0-0 (2) 17 erm(B) 15 tetM
ST2081 9 0 1 8 0 9 0 1-0-187 0 ND 0 ND
ST419 5 0 1 4 0 5 0 1-0-187 0 ND 0 ND
ST199 4 0 4 0 0 4 0 1-0-187 0 ND 0 ND
ST3017 3 1 2 0 0 3 0 1-0-187 0 ND 0 ND
ST15414
2
1
1
0
2
0
0
0-0-0
0
ND
0
ND
GPSC146
ST994
30
15
9
6
0
30
0
2-4-0 (29); new-4-0 (1)
0
ND
0
ND
GPSC1
ST320
5
2
1
2
0
5
5
13-11-16
5
erm(B), mefA
5
tetM
GPSC11
ST193
4
1
0
3
0
4
0
2-0-2 (2); 2-0-3 (1)
4
erm(B)
3
tetM
GPSC10
ST276
4
0
4
0
0
4
4
17-39-18
4
erm(B)
4
ND
GPSC109
ST13096
4
2
2
0
0
4
0
1-4-3
0
ND
0
ND
GPSC99
ST1848
3
0
0
3
0
3
0
New-44-0 (2); 2-44-2 (1)
3
erm(B)
3
tetM
GPSC10 ST15077 2 2 0 0 0 2 2 17-89-18 2 erm(B) 2 tetM

*GPSC, global pneumococcal sequence cluster; IPD, invasive pneumococcal disease; ND, not detected; PBP, penicillin-binding protein; PCV, pneumococcal conjugate vaccine; ST, sequence type.

Main Article

Page created: May 22, 2022
Page updated: July 20, 2022
Page reviewed: July 20, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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