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Volume 28, Number 8—August 2022
Research

Invasive Pneumococcal Disease and Long-Term Mortality Rates in Adults, Alberta, Canada

Kristen A. Versluys, Dean T. EurichComments to Author , Thomas J. Marrie, and Gregory J. Tyrrell
Author affiliations: University of Alberta, Edmonton, Alberta, Canada (K.A. Versluys, D.T. Eurich, G.T. Tyrrell); Dalhousie University, Halifax, Nova Scotia, Canada (T.J. Marrie); Provincial Laboratory for Public Health, Edmonton (G.T. Tyrrell)

Main Article

Table 2

Death outcomes of invasive pneumococcal disease (IPD) patients compared with age- and sex-matched controls, Alberta, Canada*

Time, days Controls
 Case-patients
 log-rank test value, p value
No. positive/no. tested (%) No. events/ 1,000 PYs No. positive/no. tested (%) No. events/ 1,000 PYs
OR (95% CI), p value
 HR (95% CI), p value
Unadjusted Adjusted Unadjusted Adjusted
<30
 348/8,837 (3.9)
 510
614/4,522 (13.6)
 1,915
3.83 (3.34–4.39), <0.001
 4.08 (3.54–4.69), <0.001
 431.40, <0.001
 3.65 (3.20‒4.17), <0.001
 3.75 (3.29‒4.28), <0.001
30–90 220/8,459 (2.6) 107 149/3,888 (3.8) 158 1.49 (1.21–1.84), <0.001 1.58 (1.28–1.96), <0.001 14.09, <0.001 1.49 (1.21‒1.83), <0.001 1.56 (1.27‒1.93), <0.001
>90
 2,086/8,236 (25.3)
 37
1,174/3,733 (31.4)
 49
1.35 (1.24–1.47), <0.001
 1.49 (1.36–1.64), <0.001
 57.44, <0.001
 1.32 (1.23‒1.42), <0.001
 1.43 (1.33‒1.54) <0.001
Overall 2,654/8,837 (30.0) 47 1,937/4,522 (42.8) 81 1.75 (1.62–1.88), <0.001 1.97 (1.81–2.14), <0.001 291.34, <0.001 1.66 (1.56‒1.76), <0.001 1.77 (1.67‒1.88), <0.001

*HR, hazard ratio; OR, odds ratio, PY, person-year.

Main Article

Page created: July 11, 2022
Page updated: July 20, 2022
Page reviewed: July 20, 2022
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