TY - JOUR AU - Bradley, Kennedy AU - Le-Mahajan, Audrey AU - Morris, Beth AU - Peritz, Tiina AU - Chiller, Tom AU - Forsberg, Kaitlin AU - Nunnally, Natalie AU - Lockhart, Shawn AU - Gold, Jeremy A.W. AU - Gould, Jane T1 - Fatal Fungicide-Associated Triazole-Resistant Aspergillus fumigatus Infection, Pennsylvania, USA T2 - Emerging Infectious Disease journal PY - 2022 VL - 28 IS - 9 SP - 1904 SN - 1080-6059 AB - We report a fatal infection in a 65-year-old immunocompromised male patient caused by pan-triazole–resistant Aspergillus fumigatus containing a TR34/L98H genetic mutation linked to agricultural fungicide use. Clinical and environmental surveillance of triazole-resistant A. fumigatus is needed in the United States to prevent spread and guide healthcare and agricultural practices. KW - Fungi KW - antimicrobial resistance KW - respiratory infections KW - Aspergillus fumigatus KW - antifungal drug resistance KW - invasive mold infection KW - triazoles KW - agriculture KW - Pennsylvania KW - United States DO - 10.3201/eid2809.220517 UR - https://wwwnc.cdc.gov/eid/article/28/9/22-0517_article ER - End of Reference