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Volume 29, Number 3—March 2023
Research

Clonal Dissemination of Antifungal-Resistant Candida haemulonii, China

Xinfei Chen, Xinmiao Jia, Jian Bing, Han Zhang, Nan Hong, Yun Liu, Haiyang Xi, Weiping Wang, Zhiyong Liu, Qiangqiang Zhang, Li Li, Mei Kang, Yuling Xiao, Bin Yang, Yulan Lin, Hui Xu, Xin Fan, Jingjing Huang, Jie Gong, Juan Xu, Xiuli Xie, Wenhang Yang, Ge Zhang, Jingjia Zhang, Wei Kang, He Wang, Xin Hou, Meng Xiao1Comments to Author , and Yingchun Xu1Comments to Author 
Author affiliations: Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X. Chen, X. Jia, H. Zhang, J. Huang, X. Xie, W. Yang, G. Zhang, J. Zhang, W. Kang, M. Xiao, Y. Xu); State Key Laboratory of Complex Severe and Rare Diseases and Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing (X. Chen, X. Jia, H. Zhang, J. Huang, X. Xie, W. Yang, G. Zhang, J. Zhang, W. Kang, M. Xiao, Y. Xu); Fudan University, Shanghai, China (J. Bing, Q. Zhang, L. Li); Nanjing University School of Medicine, Nanjing, China (N. Hong, H. Xi, W. Wang); Changhai Hospital, Shanghai (Y. Liu); Southwest Hospital Affiliated the Third Military Medical University, Chongqing, China (Z. Liu); Sichuan University, Chengdu, China (M. Kang, Y. Xiao); The First Affiliated Hospital of Fujian Medical University, Fuzhou, China (B. Yang, Y. Lin); The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (H. Xu); Capital Medical University, Beijing (X. Fan); Chinese Center for Disease Control and Prevention, Beijing (J. Gong, J. Xu); Dynamiker Sub-Center of Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Disease, Tianjin, China (H. Wang); Peking University Third Hospital, Beijing (X. Hou)

Main Article

Table

Distribution of noteworthy Erg11p substitutions among 4 clades of Candida haemulonii strains studied as part of an investigation of antifungal-resistant C. haemulonii, China

Clade/ geographic origin Erg11p substitutions
 No. isolates
Y132F V125A F126L G307A
Clade 1
International Y N N N 8
China Y N N N 5
Y N N Y 7
Y Y N N 1
Y
 N
 Y
 Y
 1
Clade 2
China
 Y
 N
 N
 N
 3
Clade 3
China
 Y
 Y
 Y
 N
 6
Clade 4
China Y N N N 7
Y N Y N 2
Y N N Y 1

Main Article

1These senior authors contributed equally to this article.

Page created: January 06, 2023
Page updated: February 19, 2023
Page reviewed: February 19, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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