TY - JOUR AU - Michalak, Kathleen AU - Austin, Connie AU - Diesel, Sandy AU - Bacon, J. Maichle AU - Zimmerman, Phil AU - Maslow, Joel N. T1 - Mycobacterium tuberculosis infection as a Zoonotic Disease: Transmission between Humans and Elephants T2 - Emerging Infectious Disease journal PY - 1998 VL - 4 IS - 2 SP - 283 SN - 1080-6059 AB - Between 1994 and 1996, three elephants from an exotic animal farm in Illinois died of pulmonary disease due to Mycobacterium tuberculosis. In October 1996, a fourth living elephant was culture-positive for M. tuberculosis. Twenty-two handlers at the farm were screened for tuberculosis (TB); eleven had positive reactions to intradermal injection with purified protein derivative. One had smear-negative, culture-positive active TB. DNA fingerprint comparison by IS6110 and TBN12 typing showed that the isolates from the four elephants and the handler with active TB were the same strain. This investigation indicates transmission of M. tuberculosis between humans and elephants. KW - United States DO - 10.3201/eid0402.980217 UR - https://wwwnc.cdc.gov/eid/article/4/2/98-0217_article ER - End of Reference