Influence of Host Genetics on the Severity of Coccidioidomycosis
Leslie Louie*

, Susanna Ng*, Rana Hajjeh†, Royce Johnson‡, Duc Vugia§, S. Benson Werner§, Ronald Talbot¶, and William Klitz*
Author affiliations: *University of California, Berkeley, California, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡Kern Medical Center, Bakersfield, California, USA; §California Department of Health Services, Berkeley, California, USA; ¶Kern County Public Health Department, Bakersfield, California, USA
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Table 2
Hardy-Weinberg test results (p values) for HLA class II loci, by ethnicity and severity of diseasea
Cases |
DRB1 |
DQA1 |
DQB1 |
DPB1 |
N |
Hispanic, Severe |
0.34 |
0.18 |
0.38 |
0.27 |
50 |
Hispanic, Mild |
0.12 |
0.11 |
0.002 |
0.045 |
32 |
Caucasian, Severe |
0.09 |
0.14 |
0.38 |
0.008 |
27 |
Caucasian, Mild |
0.12 |
0.14 |
0.11 |
0.022 |
50 |
African-American, Severe |
0.63 |
0.80 |
0.67 |
0.31 |
2 |
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Page created: December 15, 2010
Page updated: December 15, 2010
Page reviewed: December 15, 2010
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