Volume 5, Number 5—October 1999
Dispatch
Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study
Hester E. de Melker
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
Table 2
Diphtheria immunity in a sample of persons ≤79 years of age with low vaccine coverage, the Netherlands
| <0.01 IU/ml | 0.01-0.1 IU/ml | ≥0.1 IU/ml | Geometric mean titer | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sample | No. | (95% CIa) | (95% CI) | (95% CI) | (95% CI) | ||||
| OR | |||||||||
| Overall | 233 | 60.9 | (42.9-78.9) | 12.4 | (6.0-18.7) | 26.7 | (13.8-39.7) | 0.02 | (0.01-0.04) |
| Men | 116 | 69.7 | (54.2-85.2) | 10.4 | (4.2-16.6) | 19.9 | (8.2-31.5) | 0.01 | (0.01-0.03) |
| Women | 117 | 52.3 | (27.7-76.8) | 15.0 | (6.9-23.2) | 32.7 | (15.3-50.1) | 0.03 | (0.01-0.06) |
| NMCR | |||||||||
| Overall | 1,259 | 17.5 | (15.5-19.4) | 25.2 | (21.3-29.2) | 57.3 | (52.2-62.4) | 0.10 | (0.09-0.12) |
| Men | 590 | 11.5 | (8.2-14.8) | 25.5 | (20.5-30.6) | 63.0 | (55.4-70.5) | 0.14 | (0.13-0.16) |
| Women | 669 | 21.7 | (18.0-25.4) | 25.0 | (21.2-28.9) | 53.3 | (48.6-58.0) | 0.08 | (0.07-0.10) |
| TLVC | |||||||||
| Overall | 1,492 | 24.3 | (20.5-28.0) | 23.6 | (20.1-27.1) | 52.1 | (48.2-56.0) | 0.08 | (0.07-0.09) |
| Men | 706 | 20.6 | (16.6-24.7) | 23.4 | (18.9-27.8) | 56.0 | (50.3-61.7) | 0.10 | (0.08-0.12) |
| Women | 786 | 26.7 | (21.1-32.4) | 23.3 | (19.9-26.7) | 50.0 | (45.3-54.7) | 0.07 | (0.06-0.09) |
aOR, orthodox reformed; NMCR, Not member of religious communities; TLVC, total low vaccine coverage.
bCI, confidence interval
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