Volume 5, Number 5—October 1999
Dispatch
Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study
Hester E. de Melker
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
Table 3
Age-specific prevalence of diphtheria immunity and geometric mean titers for children £ 14 years of age and for men and women ≤79 years of age in a nationwide sample, the Netherlands
| Age group (yrs) | <0.01 IU/ml | 0.01-0.1 IU/ml | ≥0.1 IU/ml | Geometric mean titer | |||||
|---|---|---|---|---|---|---|---|---|---|
| No. | (95% CIa) | (95% CI) | (95% CI) | (95% CI) | |||||
| <1 | 187 | 3.7 | (1.1-6.4) | 25.5 | (18.6-32.4) | 70.7 | (63.4-78.1) | 0.19 | (0.15-0.24) |
| 1 | 185 | 1.2 | (0.0-3.0) | 9.9 | (5.4-14.3) | 88.9 | (84.3-93.5) | 0.57 | (0.45-0.72) |
| 2 | 156 | 1.9 | (0.1-3.7) | 34.9 | (24.2-45.5) | 63.3 | (52.9-73.6) | 0.15 | (0.12-0.19) |
| 3 | 215 | 1.7 | (0.1-3.3) | 35.5 | (27.7-43.3) | 62.8 | (54.7-70.9) | 0.16 | (0.12-0.22) |
| 4 | 153 | 0.6 | (0.0-1.7) | 8.7 | (3.7-13.7) | 90.7 | (85.7-95.7) | 0.81 | (0.60-1.10) |
| 5 | 102 | 1.4 | (0.0-3.3) | 6.3 | (1.9-10.7) | 92.3 | (87.7-97.0) | 0.43 | (0.35-0.52) |
| 6 | 121 | 0.9 | (0.0-2.6) | 20.0 | (11.7-28.3) | 79.1 | (70.9-87.4) | 0.26 | (0.21-0.34) |
| 7 | 101 | 2.3 | (0.0-5.4) | 31.8 | (20.3-43.3) | 65.9 | (54.7-77.2) | 0.16 | (0.13-0.20) |
| 8 | 127 | 0.7 | (0.0-2.0) | 23.6 | (14.9-32.3) | 75.8 | (66.9-84.6) | 0.28 | (0.20-0.38) |
| 9 | 97 | 0.0 | (0.0-0.0) | 11.8 | (3.2-20.4) | 88.2 | (79.6-96.8) | 0.71 | (0.51-0.99) |
| 10 | 113 | 0.7 | (0.0-2.1) | 6.7 | (1.9-11.5) | 92.6 | (87.7-97.5) | 0.54 | (0.42-0.69) |
| 11 | 111 | 0.7 | (0.0-1.9) | 8.3 | (3.5-13.2) | 91.0 | (85.8-96.2) | 0.36 | (0.30-0.44) |
| 12 | 122 | 0.6 | (0.0-1.9) | 17.0 | (9.2-24.8) | 82.4 | (74.2-90.5) | 0.28 | (0.22-0.35) |
| 13 | 126 | 0.0 | (0.0-0.0) | 27.3 | (18.0-36.7) | 72.7 | (63.3-82.0) | 0.23 | (0.18-0.29) |
| 14 | 102 | 0.4 | (0.0-1.1) | 26.7 | (14.0-39.3) | 72.9 | (60.3-85.6) | 0.22 | (0.15-0.31) |
| Men | |||||||||
| <1 | 104 | 3.5 | (0.04-7.0) | 25.2 | (15.8-34.6) | 71.3 | (61.4-81.2) | 0.18 | (0.13-0.24) |
| 1-4 | 376 | 1.8 | (0.5-3.1) | 22.9 | (17.0-28.8) | 75.3 | (69.1-81.5) | 0.31 | (0.25-0.38) |
| 5-9 | 296 | 0.6 | (0.0-1.4) | 16.9 | (12.4-21.4) | 82.5 | (77.9-87.1) | 0.34 | (0.28-0.40) |
| 10-14 | 280 | 0.6 | (0.0-1.7) | 16.5 | (11.7-21.3) | 83.0 | (78.0-88.0) | 0.32 | (0.27-0.38) |
| 15-19 | 209 | 1.0 | (0.0-2.4) | 25.8 | (19.7-31.9) | 73.1 | (67.1-79.1) | 0.19 | (0.16-0.23) |
| 20-24 | 139 | 4.0 | (0.4-7.6) | 25.5 | (17.8-33.2) | 70.5 | (62.0-79.0) | 0.15 | (0.12-0.19) |
| 25-29 | 150 | 2.9 | (0.0-6.2) | 30.6 | (21.7-39.5) | 66.5 | (56.9-76.1) | 0.18 | (0.14-0.24) |
| 30-34 | 188 | 7.0 | (1.6-12.4) | 31.5 | (23.0-40.0) | 61.5 | (52.1-70.9) | 0.14 | (0.10-0.19) |
| 35-39 | 220 | 5.1 | (1.3-8.9) | 27.4 | (20.7-34.1) | 67.5 | (60.8-74.2) | 0.18 | (0.14-0.23) |
| 40-44 | 230 | 3.8 | (1.1-6.5) | 16.3 | (11.0-21.6) | 79.9 | (73.9-85.9) | 0.25 | (0.20-0.31) |
| 45-49 | 208 | 13.7 | (7.8-19.6) | 26.6 | (21.4-31.8) | 59.7 | (51.8-67.6) | 0.13 | (0.09-0.18) |
| 50-54 | 228 | 15.0 | (10.4-19.6) | 31.1 | (24.7-37.5) | 53.9 | (46.5-61.3) | 0.10 | (0.08-0.13) |
| 55-59 | 251 | 8.8 | (4.0-13.6) | 38.8 | (32.1-45.5) | 52.4 | (46.0-58.8) | 0.10 | (0.08-0.12) |
| 60-64 | 216 | 10.3 | (6.2-14.4) | 52.3 | (43.8-60.8) | 37.4 | (29.9-44.9) | 0.07 | (0.06-0.09) |
| 65-69 | 200 | 26.5 | (19.6-33.4) | 39.4 | (30.4-48.4) | 34.1 | (26.2-42.0) | 0.05 | (0.04-0.06) |
| 70-74 | 193 | 46.2 | (36.9-55.5) | 26.6 | (19.2-34.0) | 27.1 | (19.2-35.2) | 0.03 | (0.02-0.04) |
| 75-79 | 156 | 45.0 | (35.8-54.2) | 26.2 | (17.8-34.6) | 28.8 | (20.8-36.8) | 0.03 | (0.02-0.04) |
| Women | |||||||||
| <1 | 83 | 4.2 | (0.0-8.9) | 26.6 | (13.7-39.5) | 69.3 | (56.7-81.9) | 0.19 | (0.13-0.27) |
| 1-4 | 333 | 2.2 | (0.5-3.9) | 22.2 | (16.7-27.7) | 75.6 | (70.0-81.2) | 0.30 | (0.25-0.37) |
| 5-9 | 252 | 1.8 | (0.0-3.7) | 23.8 | (16.2-31.4) | 74.5 | (68.2-80.8) | 0.29 | (0.24-0.36) |
| 10-14 | 294 | 0.3 | (0.0-0.8) | 18.6 | (12.9-24.3) | 81.1 | (75.4-86.8) | 0.29 | (0.24-0.33) |
| 15-19 | 243 | 0.7 | (0.0-1.7) | 28.2 | (21.9-34.5) | 71.1 | (64.8-77.4) | 0.17 | (0.15-0.20) |
| 20-24 | 199 | 2.8 | (0.4-5.2) | 31.3 | (23.6-39.0) | 65.9 | (58.3-73.5) | 0.14 | (0.12-0.18) |
| 25-29 | 226 | 5.0 | (1.5-8.5) | 27.1 | (20.3-33.9) | 67.9 | (60.5-75.3) | 0.14 | (0.11-0.18) |
| 30-34 | 244 | 10.0 | (5.7-14.3) | 36.9 | (30.5-43.3) | 53.0 | (47.3-58.7) | 0.11 | (0.09-0.13) |
| 35-39 | 282 | 5.6 | (2.5-8.7) | 37.0 | (29.6-44.4) | 57.4 | (50.6-64.2) | 0.13 | (0.11-0.15) |
| 40-44 | 247 | 8.7 | (4.8-12.6) | 24.4 | (18.5-30.3) | 66.9 | (60.9-72.9) | 0.16 | (0.12-0.20) |
| 45-49 | 261 | 22.0 | (15.8-28.2) | 37.6 | (30.6-44.6) | 40.3 | (32.3-48.3) | 0.06 | (0.04-0.08) |
| 50-54 | 264 | 28.2 | (20.2-36.2) | 41.7 | (34.5-48.9) | 30.1 | (23.0-37.2) | 0.04 | (0.03-0.05) |
| 55-59 | 250 | 22.3 | (16.3-28.3) | 49.7 | (43.6-55.8) | 28.0 | (22.3-33.7) | 0.04 | (0.03-0.05) |
| 60-64 | 237 | 29.2 | (22.9-35.5) | 45.9 | (39.7-52.1) | 24.8 | (19.0-30.6) | 0.03 | (0.02-0.04) |
| 65-69 | 263 | 38.0 | (30.6-45.4) | 34.3 | (29.0-39.6) | 27.7 | (21.3-34.1) | 0.03 | (0.02-0.05) |
| 70-74 | 218 | 58.2 | (50.8-65.6) | 25.0 | (18.9-31.1) | 16.8 | (11.0-22.6) | 0.02 | (0.01-0.02) |
| 75-79 | 175 | 52.7 | (43.8-61.6) | 26.6 | (19.4-33.8) | 20.7 | (12.7-28.7) | 0.02 | (0.01-0.03) |
aCI, confidence interval.
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Page reviewed: December 15, 2010
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