Volume 5, Number 5—October 1999
Dispatch
Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study
Hester E. de Melker
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
, G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
Table 6
Diphtheria immunity for persons in a nationwide sample who were completely vaccinated in the national immunization program and received the sixth diphtheria vaccination at 8 or 9 years of age, the Netherlands
| Samplea | <0.01 IU/ml | 0.01-0.1 IU/ml | ≥0.1 IU/ml | Geometric mean titer(UI/ml) | |||||
|---|---|---|---|---|---|---|---|---|---|
| (yrs) | No. | (95% CIb) | (95% CI) | (95% CI) | (95% CI) | ||||
| NRE | |||||||||
| 10-14 | 392 | 0.0 | -- | 17.5 | (12.8-22.1) | 82.5 | (77.9-87.1) | 0.30 | (0.26-0.34) |
| 15-19 | 282 | 0.4 | (0.0-1.3) | 30.1 | (23.7-36.5) | 69.4 | (63.2-75.7) | 0.17 | (0.14-0.21) |
| 20-24 | 155 | 1.2 | (0.0-3.0) | 29.4 | (20.7-38.2) | 69.4 | (60.7-78.1) | 0.16 | (0.12-0.19) |
| 25-29 | 80 | 1.6 | (0.0-3.7) | 28.3 | (17.2-39.4) | 70.2 | (58.7-81.6) | 0.14 | (0.11-0.18) |
| 30-34 | 52 | 4.3 | (0.0-9.2) | 54.0 | (39.3-68.8) | 41.7 | (27.3-56.1) | 0.09 | (0.07-0.13) |
| RE | |||||||||
| 20-34 | 37 | 0.0 | -- | 19.0 | (3.2-34.9) | 81.0 | (65.1-96.8) | 0.29 | (0.18-0.46) |
aNRE, no evidence of revaccination; RE, evidence of revaccination
bCI, confidence interval.
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