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Volume 7, Number 4—August 2001
THEME ISSUE
West Nile Virus
West Nile Virus

Partial Genetic Characterization of West Nile Virus Strains, New York State, 2000

Gregory D. EbelComments to Author , Alan P. Dupuis, Kiet Ngo, David Nicholas, Elizabeth Kauffman, Susan A. Jones, Donna Young, Joseph Maffei, Pei-Yong Shi, Kristen Bernard, and Laura D. Kramer
Author affiliations: New York State Department of Health, Slingerlands, New York, USA

Main Article

Table 3

Nucleotide substitutions in strains studied

Position
Strain 1285 1332 1449 1899 1974 2280 2321 2359 2386 2424
NY99-EQHS C U C U C U C C A C
3000017 - - - - U C - - - U
3000259 - - - - - - - - - -
3000548 - C - - - - - - - -
3000622 - - U - - - - - - -
3100271 - - - - - - - - - -
3100352 - - - C U - - - - -
3100365 - - - - U - - - - -
842 - - - - - - - U G -
2741 - - - - - - - - - -
3282 U - - - - - - - - -
3356 U - - - U - U - - -

Position numbers correspond to Lanciotti et al. (1).

Main Article

References
  1. Lanciotti  RS, Roehrig  JT, Deubel  V, Smith  J, Parker  M, Steele  K, Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States. Science. 1999;286:23337. DOIPubMedGoogle Scholar
  2. Baqar  S, Hayes  CG, Murphy  JR, Watts  DM. Vertical transmission of West Nile virus by Culex and Aedes species mosquitoes. Am J Trop Med Hyg. 1993;48:75762.PubMedGoogle Scholar
  3. Rappole  JH, Derrickson  SR, Hubalek  Z. Migratory birds and spread of West Nile virus in the Western Hemisphere. Emerg Infect Dis. 2000;6:31928. DOIPubMedGoogle Scholar
  4. Komar  N. West Nile viral encephalitis. Rev Sci Tech. 2000;19:16676.PubMedGoogle Scholar
  5. Steele  KE, Linn  MJ, Schoepp  RJ, Komar  N, Geisbert  TW, Manduca  RM, Pathology of fatal West Nile virus infections in native and exotic birds during the 1999 outbreak in New York City, New York. Vet Pathol. 2000;37:20824. DOIPubMedGoogle Scholar
  6. Holland  JJ, Spindler  K, Horodyski  F, Grabau  E, Nichol  S, VandePol  S. Rapid evolution of RNA genomes. Science. 1982;215:157785. DOIPubMedGoogle Scholar
  7. Steinhauer  DA, Holland  JJ. Rapid evolution of RNA viruses. Annu Rev Microbiol. 1987;41:40933. DOIPubMedGoogle Scholar
  8. Garmendia  AE, Van Kruiningen  HJ, French  RA, Anderson  JF, Andreadis  TG, Kumar  A, Recovery and identification of West Nile virus from a hawk in winter. J Clin Microbiol. 2000;38:31101.PubMedGoogle Scholar
  9. Kumar  S, Tamura  K, Nei  M. MEGA: molecular evolutionary genetics analysis. 16802. University Park (PA): Pennsylvania State University Press; 1993.
  10. Kramer  LD, Presser  SB, Hardy  JL, Jackson  AO. Genotypic and phenotypic variation of selected Saint Louis encephalitis viral strains isolated in California. Am J Trop Med Hyg. 1997;57:2229.PubMedGoogle Scholar
  11. Harris  E, Roberts  TG, Smith  L, Selle  J, Kramer  LD, Valle  S, Typing of dengue viruses in clinical specimens and mosquitoes by single-tube multiplex reverse transcriptase PCR. J Clin Microbiol. 1998;36:26349.PubMedGoogle Scholar
  12. Powers  AM, Oberste  MS, Brault  AC, Rico-Hesse  R, Schmura  SM, Smith  JF, Repeated emergence of epidemic/epizootic Venezuelan equine encephalitis from a single genotype of enzootic subtype ID virus. J Virol. 1997;71:6697705.PubMedGoogle Scholar
  13. Ebel  GD, Foppa  I, Spielman  A, Telford  SR. A focus of deer tick virus transmission in the northcentral United States. Emerg Infect Dis. 1999;5:5704. DOIPubMedGoogle Scholar
  14. Duarte  EA, Novella  IS, Weaver  SC, Domingo  E, Wain-Hobson  S, Clarke  DK, RNA virus quasispecies: significance for viral disease and epidemiology. Infect Agents Dis. 1994;3:20114.PubMedGoogle Scholar
  15. Holland  JJ, de la Torre  JC, Steinhauer  DA. RNA virus populations as quasispecies. Curr Top Microbiol Immunol. 1992;176:120. DOIPubMedGoogle Scholar
  16. Steinhauer  DA, Domingo  E, Holland  JJ. Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase. Gene. 1992;122:2818. DOIPubMedGoogle Scholar
  17. Zanotto  PMDA, Gould  EA, Gao  GF, Harvey  PH, Holmes  EC. Population dynamics of flaviviruses revealed by molecular phylogenies. Proc Natl Acad Sci U S A. 1996;93:54853. DOIPubMedGoogle Scholar
  18. Pisano  MR, Tolou  H. The topotype notion and the quasispecies concept: The yellow fever virus as example. Travaux Scientifiques des Chercheurs du Service de Sante des Armees 1996;69-70.
  19. Duarte  E, Clarke  D, Moya  A, Domingo  E, Holland  J. Rapid fitness losses in mammalian RNA virus clones due to Mueller's ratchet. Proc Natl Acad Sci U S A. 1992;89:60159. DOIPubMedGoogle Scholar

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