Figure. . Pulsed-field gel electrophoresis (PFGE) patterns of SmaI-digested genomic DNA of Streptococcus pneumoniae isolates. Seven distinct patterns, including A and its subtypes (A0 to A5) and B to G, are shown. Labels indicate the PFGE pattern, hospital source, and serotype. Lane 1: molecular weight markers; lane 2: S. pneumoniae ATCC 49619; lanes 3 to 8: ciprofloxacin-resistant isolates; lane 9: Spanish 23F clone (ATCC 700669); lanes 10-19: ciprofloxacin-sensitive isolates.