TY - JOUR AU - Moses, Allon E. AU - Goldberg, Sara AU - Korenman, Zinaida AU - Ravins, Miriam AU - Hanski, Emanuel AU - Shapiro, Mervyn T1 - Invasive Group A Streptococcal Infections, Israel T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 4 SP - 421 SN - 1080-6059 AB - We conducted a prospective, nationwide, population-based study of invasive group A streptococcal infections in Israel. We identified 409 patients (median age 27 years; range <1-92), for an annual incidence of 3.7/100,000 (11/100,000 in Jerusalem). The mortality rate was 5%. Bacteremia occurred in 125 cases (31%). The most common illnesses were soft-tissue infection (63%) and primary bacteremia (14%). Thirty percent of patients had no identifiable risk factors for infection. Eighty-seven percent of pharyngeal carriers had the same serotype as the index patient. M types included M3 (25%), M28 (10%), and M-nontypable (33%). A marked paucity of M1 serotype (1.2%) was detected. The results highlighted concentrated pockets of invasive disease in the Jewish orthodox community (annual incidence 16/100,000). KW - Streptococcus pyogenes KW - prospective study KW - population-based epidemiology KW - surveillance KW - invasive disease KW - Israel DO - 10.3201/eid0804.010278 UR - https://wwwnc.cdc.gov/eid/article/8/4/01-0278_article ER - End of Reference