TY - JOUR AU - Lokugamage, Kumari AU - Kariwa, Hiroaki AU - Hayasaka, Daisuke AU - Cui, Bai Zhong AU - Iwasaki, Takuya AU - Lokugamage, Nandadeva AU - Ivanov, Leonid I. AU - Volkov, Vladimir I. AU - Demenev, Vladimir A. AU - Slonova, Raisa AU - Kompanets, Galina AU - Kushnaryova, Tatyana AU - Kurata, Takeshi AU - Maeda, Kenji AU - Araki, Koichi AU - Mizutani, Tetsuya AU - Yoshimatsu, Kumiko AU - Arikawa, Jiro AU - Takashima, Ikuo T1 - Genetic Characterization of Hantaviruses Transmitted by the Korean Field Mouse (Apodemus peninsulae), Far East Russia T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 8 SP - 768 SN - 1080-6059 AB - In an epizootiologic survey of 122 rodents captured in Vladivostok, Russia, antibodies positive for hantavirus were found in Apodemus peninsulae (4/70), A. agrarius (1/39), and Clethrionomys rufocanus (1/8). The hantavirus sequences identified in two seropositive A. peninsulae and two patients with hemorrhagic fever with renal syndrome (HFRS) from the Primorye region of Far East Russia were designated as Solovey and Primorye, respectively. The nucleotide sequences of the Solovey, Primorye, and Amur (obtained through GenBank) sequences were closely related (>92% identity). Solovey and Primorye sequences shared 84% nucleotide identity with the prototype Hantaan 76-118. Phylogenetic analysis also indicated a close relationship between Solovey, Primorye, Amur, and other viruses identified in Russia, China, and Korea. Our findings suggest that the Korean field mouse (A. peninsulae) is the reservoir for a hantavirus that causes HFRS over a vast area of east Asia, including Far East Russia. KW - Hantavirus KW - Apodemus peninsulae KW - hemorrhagic fever with renal syndrome KW - HFRS KW - Far East Russia KW - Russia DO - 10.3201/eid0808.010494 UR - https://wwwnc.cdc.gov/eid/article/8/8/01-0494_article ER - End of Reference