TY - JOUR
AU - Gillespie, Iain
AU - O’Brien, Sarah J.
AU - Frost, Jennifer A.
AU - Adak, Goutam K.
AU - Phong, Le Hong
AU - Swan, Anthony V.
AU - Painter, Michael J.
AU - Neal, Keith R.
T1 - A Case-Case Comparison of Campylobacter coli and Campylobacter jejuni Infection: A Tool for Generating Hypotheses
T2 - Emerging Infectious Disease journal
PY - 2002
VL - 8
IS - 9
SP - 937
SN - 1080-6059
AB - Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used case-case analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and Wales. Persons with C. coli infection were more likely to have drunk bottled water than were those with C. jejuni infection and, in general, were more likely to have eaten pâté. Important differences in exposures were identified for these two Campylobacter species. Exposures that are a risk for infection for both comparison groups might not be identified or might be underestimated by case-case analysis. Similarly, the magnitude or direction of population risk cannot be assessed accurately. Nevertheless, our findings suggest that case-control studies should be conducted at the species level.
KW - Campylobacter
KW - epidemiology
KW - surveillance
KW - hypothesis generation
KW - risk
KW - United Kingdom
DO - 10.3201/eid0809.010187
UR - https://wwwnc.cdc.gov/eid/article/8/9/01-0187_article
ER - End of Reference