TY - JOUR AU - Borer, Abraham AU - Gilad, Jacob AU - Yagupsky, Pablo AU - Peled, Nechama AU - Porat, Nurith AU - Trefler, Ronit AU - Shprecher-Levy, Hannah AU - Riesenberg, Klaris AU - Shipman, Miriam AU - Schlaeffer, Francisc T1 - Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 9 SP - 966 SN - 1080-6059 AB - Methicillin-resistant Staphylococcus aureus (MRSA) has recently been reported to emerge in the community setting. We describe the investigation and control of a community-acquired outbreak of MRSA skin infections in a closed community of institutionalized adults with developmental disabilities. In a 9-month period in 1997, 20 (71%) of 28 residents had 73 infectious episodes. Of the cultures, 60% and 32% obtained from residents and personnel, respectively, grew S. aureus; 96% and 27% were MRSA. All isolates were genetically related by pulsed-field gel electrophoresis and belonged to a phage type not previously described in the region. No known risk factors for MRSA acquisition were found. However, 58 antibiotic courses had been administered to 16 residents during the preceding 9 months. Infection control measures, antibiotic restriction, and appropriate therapy resulted in successful termination of this outbreak. Selective antibiotic pressure may result in the emergence, persistence, and dissemination of MRSA strains, causing prolonged disease. KW - Israel DO - 10.3201/eid0809.020300 UR - https://wwwnc.cdc.gov/eid/article/8/9/02-0300_article ER - End of Reference