Volume 9, Number 12—December 2003
Research
Mycobacterium abscessus and Children with Cystic Fibrosis
Isabelle Sermet-Gaudelus*, Muriel Le Bourgeois*, Catherine Pierre-Audigier*, Catherine Offredo*, Didier Guillemot†, Sophie Halley*, Chantal Akoua-Koffi*, Véronique Vincent†, Valérie Sivadon-Tardy‡, Agnès Ferroni*, Patrick Berche*, Pierre Scheinmann*, Gérard Lenoir*, and Jean-Louis Gaillard‡
Table
Chronology of case-patients with Mycobacterium abcessus isolationa
| Case no. | Age (y)/sex | Date of first isolation | No. of pos. cultures/total AFB culturesb | No. of pos. AFB smears/total AFB smearsb,c | hsp65 genomovard | Sputum microbiologic resultse | |
|---|---|---|---|---|---|---|---|
| 1 |
2.5 / M |
Jan 1996 |
37/48 |
19/31 |
(+++) |
-6 |
Negative |
| 2 |
13 / F |
Feb 1996 |
2/14 |
0/9 |
T |
Pseudomonas aeruginosa |
|
| 3 |
15 / F |
Apr 1996 |
3/41 |
0/21 |
-5a |
P. aeruginosa |
|
| 4 |
16 / M |
Apr 1996 |
5/8 |
1/6 |
(+) |
T |
P. aeruginosa, Staphylococcus aureus, Aspergillus fumigatus |
| 5 |
14 / F |
May 1996 |
8/11 |
4/8 |
(++) |
T |
P. aeruginosa, S. aureus, A. fumigatus |
| 6 |
10 / M |
May 1996 |
4/25 |
0/12 |
T |
P. aeruginosa, Alcaligenes xylosoxidans |
|
| 7 |
9 / F |
May 1996 |
8/8 |
4/7 |
(+++) |
T |
P. aeruginosa, Aspergillus fumigatus |
| 8 |
2.5 / F |
Nov 1997 |
4/6 |
2/5 |
(++) |
-5a |
Negative |
| 9 |
7 / F |
July 1998 |
2/24 |
0/7 |
-5a |
S. aureus |
|
| 10 |
17 / M |
Sept 1998 |
3/9 |
0/6 |
T |
S. aureus, Haemophilus influenzae, Stenotrophomonas maltophilia, A. fumigatus |
|
| 11 |
8 / F |
Sept 1998 |
3/12 |
0/4 |
T |
P. aeruginosa, Staphylococcus aureus |
|
| 12 |
18/F |
July 1999 |
1/5 |
0/3 |
T |
P. aeruginosa, A. fumigatus |
|
| 13 |
9/M |
Sept 1999 |
1/6 |
0/3 |
-6 |
S. aureus |
|
| 14 |
16/M |
Oct 1999 |
5/13 |
4/6 |
(+) |
-5a |
S. aureus, A. fumigatus |
| 15 | 22/F | Nov 1999 | 1/6 | 0/3 | -6 | P. aeruginosa, S. aureus | |
aAFB, acid-fast bacilli.
bSamples obtained from patients from January 1996 to December 2000; only samples obtained before the administration of antimycobacterial drugs are considered in treated patients.
cSymbols in parentheses: AFB density.
dSee Methods.
eOrganisms recovered from at least three sputum samples within the 12 months before the first isolation of M. abscessus.
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Page updated: February 07, 2011
Page reviewed: February 07, 2011
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