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Volume 9, Number 2—February 2003

Photorhabdus Species: Bioluminescent Bacteria as Human Pathogens?

John G. Gerrard*Comments to Author , Samantha McNevin†, David Alfredson*, Ross Forgan-Smith†, and Neil Fraser‡
Author affiliations: *Gold Coast Hospital, Southport, Queensland, Australia; †Queensland Medical Laboratory, West End, Queensland, Australia; ‡Harbour City Family Practice, Gladstone, Queensland, Australia

Main Article

Table 2

Published human cases of Photorhabdus infection

no. Year Country Location Age/sex Clinical Alleged vector Source of isolate
1 2001 Australia Gladstone, Queensland 39M Soft tissue infection right ankle
(professional pest controller)   Pus from ankle ulcer
2 1999 Australia Gold Coast, Queensland 78M Soft tissue infection right foot   Pus and tissue from right foot
3 (1) 1998 Australia Murwil-lumbah, New South Wales 55M Multifocal soft tissue infections (upper and lower limbs, abdomen), pneumonia   Blood, sputum, pus and tissue
4 (1) 1998 Australia Wangaratta, Victoria 50M Multifocal soft tissue infections (upper and lower limbs) Spider Pus from soft tissue abscesses
5 (1) 1998 Australia Melbourne, Victoria 90M Cough and fever   Blood
6 (1) 1994 Australia Melbourne, Victoria 11F Multifocal soft tissue infections (lower limbs and chest)   Pus and soft tissue biopsies
7 (6) 1989 USA San Antonio, Texas   Groin infection   Groin
8 (6) 1987 USA San Antonio, Texas 45M Multifocal soft tissue infection, left lower limb Spider Pus from lower limb abscess
9 (6) 1986 USA San Antonio, Texas 78M Multifocal soft tissue infection left lower limb   Pus from lower limb abscess and ulcer
10 (6) 1984 USA San Antonio, Texas 36F Disseminated bacterial infection   Submandible, abdomen
11 (6) 1979 USA Pennsyl
vania 72F     Blood, skin
12 (6) 1977 USA Maryland 80F Endocarditis   Blood

Main Article

  1. Peel  MM, Alfredson  DA, Gerrard  JG, Davis  JM, Robson  JM, McDougall  RJ, Isolation, identification, and molecular characterization of strains of Photorhabdus luminescens from infected humans in Australia. J Clin Microbiol. 1999;37:364753.PubMedGoogle Scholar
  2. Fischer-Le Saux  M, Viallard  V, Brunel  B, Normand  P, Boemare  NE. Polyphasic classification of the genus Photorhabdus and proposal of new taxa: P. luminescens subsp. luminescens subsp. nov., P. luminescens subsp. akhurstii subsp. nov., P. luminescens subsp. laumondii subsp. nov., P. temperata sp. nov., P. temperata subsp. temperata subsp. nov. and P. asymbiotica sp. nov. Int J Syst Bacteriol. 1999;49:164556. DOIPubMedGoogle Scholar
  3. Boemare  N, Givaudan  A, Brehelin  M, Laumond  C. Symbiosis and pathogenicity of nematode-bacterium complexes. Symbiosis. 1997;22:2145.
  4. ffrench-Constant RH, Bowen DJ. Novel insecticidal toxins from nematode-symbiotic bacteria. Cell Mol Life Sci. 2000;57:82833. DOIPubMedGoogle Scholar
  5. Parkhill  J, Wren  BW, Thomson  NR, Titball  RW, Holden  MT, Prentice  MB, Genome sequence of Yersinia pestis, the causative agent of plague. Nature. 2001;413:5237. DOIPubMedGoogle Scholar
  6. Farmer  JJ, Jorgensen  JH, Grimont  PAD, Ackhurst  RJ, Poinar  GO, Ageron  E, Xenorhabdus luminescens (DNA Hybridization Group 5) from human clinical specimens. J Clin Microbiol. 1989;27:1594600.PubMedGoogle Scholar
  7. Akhurst  R, Smith  K. Regulation and safety. In: Gaugler R, editor. Entomopathogenic nematology. New York: CABI Publishing; 2002. p. 311–32.
  8. Bleakley  BH, Chen  X. Survival of insect pathogenic and human clinical isolates of Photorhabdus luminescens in previously sterile soil. Can J Microbiol. 1999;45:2738. DOIPubMedGoogle Scholar

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Page updated: December 07, 2010
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