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Volume 9, Number 6—June 2003
Research

Clinical Implications of Varying Degrees of Vancomycin Susceptilibity in Methicillin-Resistant Staphylococcus aureus Bacteremia1

Mitchell J. Schwaber*†‡Comments to Author , Sharon B. Wright*†, Yehuda Carmeli*†‡, Lata Venkataraman*†, Paola C. DeGirolami*†, Aneta Gramatikova§, Trish M. Perl§, George Sakoulas*†, and Howard S. Gold*†
Author affiliations: *Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; †Harvard Medical School, Boston, Massachusetts, USA; ‡Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; §Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

Main Article

Table 2

Descriptive characteristics of cohort

Characteristic Cases, n=61 (%) Controls, n=8 (%) p
Mean age (y)
61±17
64±14
0.21
Male
37 (61)
53 (60)
1.00
Diabetes mellitus
30 (49)
34 (39)
0.24
Renal disease
20 (33)
29 (33)
1.00
Hemodialysis
10 (16)
12 (14)
0.65
Cardiovascular disease
41 (67)
56 (64)
0.73
Pulmonary disease
19 (31)
35 (40)
0.30
Hepatic disease
8 (13)
7 (8)
0.41
HIV
3 (5)
3 (3)
0.69
Prosthetic joint or valve, or permanent pacemaker
13 (21)
11 (13)
0.18
Hospitalization at same institution
<30 days preceding culture
51 (84)
66 (75)
0.23
Surgery during admission before culture
17 (28)
20 (23)
0.56
Intensive care unit stay during admission before culture
33 (54)
38 (43)
0.24
Severity of illness scorea 0.62

aSeverity of illness is based on modified McCabe criteria (23): 1, severe underlying coexisting chronic condition at imminent risk of death; 2, significant underlying coexisting chronic condition, not at imminent risk of death; 3, no significant underlying coexisting chronic condition.

Main Article

1Presented in part at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, Illinois, December 2001.

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