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Volume 9, Number 6—June 2003
Research

Children with Respiratory Disease Associated with Metapneumovirus in Hong Kong

J.S. Malik Peiris*, Wing-Hong Tang*, Kwok-Hung Chan*, Pek-Lan Khong*, Yi Guan*, Yu-Lung Lau*, and Susan S. Chiu*Comments to Author 
Author affiliations: *The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China

Main Article

Table 2

Characteristics of 32 children admitted with HMPV compared with age-matched controls with RSV and influenza Aa

Characteristics HMPV
RSV
Influenza A
p valueb
No. positive/
total (%) No. positive/
total (%) No. positive/
total (%) Overall HMPV vs. RSV HMPV vs. influenza A
Influenzalike illness in family contact
10/19 (52.6)
7/29 (24.1)
19/24 (79.1)
0.0003
0.29
0.37
Influenzalike illness in adult family contact
5/19 (26.3)
4/29 (13.8)
13/24 (54.2)
0.005
0.68
0.45
Febrile seizures
5/32 (15.6)
1/32 (3.1)
3/32 (9.4)
0.229


Congested pharynx
12/32 (37.5)
11/32 (34.4)
11/32 (34.4)
0.955


Rash
4/32 (12.5)
1/32 (3.1)
4/32 (12.5)
0.331


Enlarged liver
2/32 (6.3)
0/32 (0.0)
4/32 (12.5)
0.331


Otitis media
4/32 (12.5)
0/32 (0.0)
0/32 (0.0)
0.201


Diarrhea
2/32 (6.3)
1/32 (3.1)
3/32 (9.4)
0.586


Crepitations
18/32 (56.3)
14/32 (43.8)
3/32 (9.4)
0.0003
0.50
0.0007
Wheezing
9/32 (28.1)
12/32 (37.5)
2/32 (6.3)
0.0109
0.60
0.04
Asthma exacerbation
6/32 (18.8)
2/32 (6.3)
2/32 (6.3)
0.167


Acute bronchiolitis
3/32 (9.4)
10/32 (31.3)
0/32 (0.0)
0.0009
0.13
0.37
Pneumonia
12/32 (37.5)
5/32 (15.6)
1/32 (3.1)
0.0017
0.30
0.009
Abnormal chest x-ray
17/25 (68.0)
11/18 (61.1)
1/17 (5.9)
0.0002
0.89
0.0002
Lymphopenia (<1.5 x 109/L)
9/31 (29.0)
2/27 (7.4)
12/29 (41.4)
0.017
0.34
1.0
Neutropenia (ANC<1 x 109/L)
2/31 (6.5)
0/27 (0.0)
4/29 (13.8)
0.125


Elevated transaminases 2/15 (13.3) 0/5 (0.0) 3/11 (27.3) 0.357

aHMPV, human metapneumovirus; RSV, respiratory syncytial virus.
bp values performed using McNemar chi-square test.

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Page created: December 22, 2010
Page updated: December 22, 2010
Page reviewed: December 22, 2010
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