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Volume 11, Number 2—February 2005
Perspective

Managing Febrile Respiratory Illnesses during Hypothetical SARS Outbreaks

Kamran Khan*Comments to Author , Peter Muennig†, Michael Gardam‡, and Joshua Graff Zivin†
Author affiliations: *St. Michael’s Hospital, Toronto, Ontario, Canada; †Columbia University, New York, New York, USA; ‡University Health Network, Toronto, Ontario, Canada

Main Article

Table 3

Cost-effectiveness of strategies for managing FRIs of undetermined etiology*

Available public health strategies Monthly total
Incremental cost-effectiveness (cost per QALY gained)
Costs ($ billion)† QALY gained
Home isolation 2.13 0
Influenza testing
2.14
5,286
$1,702
Home isolation 2.13 0
Influenza testing 2.14 5,286 Dominated
Multiplex RT-PCR testing‡
2.05
8,474
Savings
Home isolation 2.13 0
SARS + influenza testing 2.19 5,280 Dominated
Influenza testing 2.14 5,286 Dominated
SARS + multiplex RT-PCR testing‡ 2.14 8,429 Dominated
Multiplex RT-PCR testing‡ 2.05 8,474 Savings

*FRI, febrile respiratory illness; QALY, quality-adjusted life-year; RT-PCR, reverse transcription–polymerase chain reaction; –, reference category.
†Shown in 2004 U.S. dollars rounded to the nearest 10 million.
‡Multiplex RT-PCR testing to detect influenza viruses A and B, respiratory syncytial viruses A and B, parainfluenza viruses 1–3, human metapneumovirus, Bordetella pertussis, Chlamydia pneumoniae, Mycoplasma pneumoniae, Legionella pneumophila, and L. micdadei.

Main Article

Page created: April 27, 2011
Page updated: April 27, 2011
Page reviewed: April 27, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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