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Volume 15, Number 2—February 2009
Research

Characteristics of 263K Scrapie Agent in Multiple Hamster Species

Kimberly D. Meade-WhiteComments to Author , Kent D. Barbian, Brent Race, Cynthia Favara, Don Gardner, Lara Taubner, Stephen Porcella, and Richard Race
Author affiliations: National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA

Main Article

Table

Average incubation period for 263K scrapie*

Hamster species† Cross-species 263K
Second passage
Third passage
Back passage‡
Dpi ± SD Titer/50 μL (1% BH) Dpi Titer/50 μL (1% BH) Dpi Titer/50 μL (1% BH) Dpi
Syrian 85 2 x 109 ND ND ND ND 79 ± 5
Turkish 91 ± 4.9 1 x 108.9 103 ± 7.2 1 x 106.7 85 ± 7.6 1 x 108.25 76 ± 0
Djungarian 155 ± 23.4 1 x 108.4 100 ± 9.0 1 x 109.6 99 ± 7.2 1 x 109.7 97 ± 7
Siberian 148 ± 26.5 1 x 108.3 117 ± 9.9 1 x107.75 114 ± 8.3 1 x 108.1 128 ± 17
Chinese 372 ± 29.1 ND 233 ± 17.9 ND 207 ± 15.2 ND 168 ± 7
Armenian 188 ± 10.4 1 x 107.35 156 ±4.8 1 x 107.75 145 ±7.5 >1 x 108.5 145 ± 18

*Dpi, days postinoculation; ND, not done; BH, brain homogenate.
†16 hamsters/species.
‡In Syrian hamster.

Main Article

Page created: December 08, 2010
Page updated: December 08, 2010
Page reviewed: December 08, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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