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Volume 3, Number 2—June 1997
Perspective

The Economic Impact of a Bioterrorist Attack: Are Prevention and Postattack Intervention Programs Justifiable?

Arnold F. Kaufmann, Martin I. MeltzerComments to Author , and George P. Schmid
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

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Figure 2

Rangesa of net savings due to postattack prophylaxis by disease and day of prophylaxis program initiation. aMaximum savings (l) were calculated by assuming a 95% effectiveness prophylaxis regimen and a 3% discount rate in determining the present value of expected lifetime earnings lost due to premature death (16) and a multiplication factor of 5 to adjust for unnecessary prophylaxis. Minimum savings (n) were calculated by assuming an 80% to 90% effectiveness regimen and a 5% discount rate and a

Figure 2. Rangesa of net savings due to postattack prophylaxis by disease and day of prophylaxis program initiation. aMaximum savings (l) were calculated by assuming a 95% effectiveness prophylaxis regimen and a 3% discount rate in determining the present value of expected lifetime earnings lost due to premature death (16) and a multiplication factor of 5 to adjust for unnecessary prophylaxis. Minimum savings (n) were calculated by assuming an 80% to 90% effectiveness regimen and a 5% discount rate and a multiplication factor of 15. In tularemia prophylaxis programs initiated on days 4-7 postattack, the minimum savings were calculated by assuming a 95% prophylaxis regimen effectiveness rather than an effectiveness of 80% to 90%.

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References
  1. Cole  LA. The specter of biological weapons.Sci Am. 1996;275:605. DOIPubMedGoogle Scholar
  2. Gochenour  WS. Aerobiology. Mil Med. 1963;128:869.PubMedGoogle Scholar
  3. Abramova  FAN, Grinberg  LM, Yampolskaya  OV, Walker  DH. Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. Proc Natl Acad Sci U S A. 1993;90:22914. DOIPubMedGoogle Scholar
  4. Benenson  AS, ed. Control of communicable diseases manual. 16th ed. Washington (DC): American Public Health Association, 1995.
  5. Messelson  M, Guillemin  J, Hugh-Jones  M, Langmuir  A, Popova  I, Shelokov  A, The Sverdlosvsk anthrax outbreak of 1979. Science. 1994;266:12028. DOIPubMedGoogle Scholar
  6. Kaufmann  AF, Fox  MD, Boyce  JM, Anderson  DC, Potter  ME, Martone  WJ, Airborne spread of brucellosis. Ann N Y Acad Sci. 1980;335:10514. DOIGoogle Scholar
  7. Olle-Goig  JE, Canela-Soler  J. An outbreak of Brucella melitensis infection by airborne transmission among laboratory workers. Am J Public Health. 1987;77:3358. DOIPubMedGoogle Scholar
  8. Staszkiewicz  J, Lewis  CM, Colville  J, Zervos  M, Band  J. Outbreak of Brucella melitensis among microbiology laboratory workers in a community hospital.J Clin Microbiol. 1991;29:28790. PubMedGoogle Scholar
  9. Trever  RW, Cluff  LE, Peeler  RN, Bennett  IL. Brucellosis I. laboratory-acquired acute infection. Arch Intern Med. 1959;103:38197.
  10. McCrumb  FR. Aerosol infection of man with Pasteurella tularensis. Bacteriol Rev. 1961;25:2627.PubMedGoogle Scholar
  11. Saslaw  S, Eigelsbach  HT, Wilson  HR, Prior  JA, Carhart  S. Tularemia vaccine study II. respiratory challenge. Arch Intern Med. 1961;107:689701.PubMedGoogle Scholar
  12. Friedlander  AM, Welkos  SL, Pitt  MLM, Ezzell  JW, Worsham  PL, Rose  KJ, Postexposure prophylaxis against experimental inhalation anthraxJ Infect Dis. 1993;167:123942.PubMedGoogle Scholar
  13. Sawyer  WD, Dangerfield  HG, Hogge  AL, Crozier  D. Antibiotic prophylaxis and therapy of airborne tularemia PubMed. Bacteriol Rev. 1966;30:5428.PubMedGoogle Scholar
  14. Solera  J, Rodriguez-Zapata  M, Geijo  P, Largo  J, Paulino  J, Saez  L, Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis.Antimicrob Agents Chemother. 1995;39:20617. PubMedGoogle Scholar
  15. Luce  BR, Manning  WG, Siegel  JE, Lipscomb  J. Estimating costs in cost-effectiveness analysis. In: Gold MR, Siegel JE, Russell LB, Weinstein MC, editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1966:176-213.
  16. Haddix  AC, Teutsch  SM, Shaffer  PA, Dunet  DO, eds. Prevention effectiveness: a guide to decision analysis and economic evaluation. New York: Oxford University Press, 1996.
  17. Lipscomb  J, Weinstein  MC, Torrance  GW. Time preference. In: Gold MR, Siegel JE, Russell LB, Weinstein MC, editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1966:214-35.
  18. U.S. Bureau of the Census. Statistical abstract of the United States: 1995. 115th ed. Washington (DC): U.S. Government Printing Office, 1996.
  19. National Center for Health Statistics. Health, United States, 1995. Hyattsville (MD):U.S.Departmentof Health and Human Services, Public Health Service, 1996.
  20. HealthCare Consultants of America, Inc. HealthCare Consultants' 1996 physicians fee and coding guide. 6th ed. Augusta (GA): HealthCare Consultants of America, Inc. 1996.
  21. Cardinale  V, ed. 1996 Drug Topics Red Book. Montvale (NJ): Medical Economics Company, Inc., 1996.
  22. Robison  LJ, Barry  PJ. The competitive firm's response to risk. New York: Macmillan, 1987.

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