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Volume 9, Number 7—July 2003
Perspective

Global Screening for Human Viral Pathogens

Norman G. Anderson*Comments to Author , John L. Gerin†, and N. Leigh Anderson‡
Author affiliations: *Viral Defense Foundation, Kensington, Maryland, USA; †Georgetown University Medical Center, Rockville, Maryland, USA; ‡Plasma Proteome Institute, Washington, D.C., USA

Main Article

Figure

Schematic representation of a process for systematic discovery of human viruses. The basic process (left vertical series of steps) depends on physical isolation and shotgun sequencing to obtain sequences of frequent and rare viruses. A series of additional steps (right box) can be added to deplete known viruses at two levels, thereby enhancing sensitivity for novel agents.

Figure. Schematic representation of a process for systematic discovery of human viruses. The basic process (left vertical series of steps) depends on physical isolation and shotgun sequencing to obtain sequences of frequent and rare viruses. A series of additional steps (right box) can be added to deplete known viruses at two levels, thereby enhancing sensitivity for novel agents.

Main Article

Page created: December 22, 2010
Page updated: December 22, 2010
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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