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Volume 18, Number 3—March 2012
Research

Using Genotyping and Geospatial Scanning to Estimate Recent Mycobacterium tuberculosis Transmission, United States

Patrick K. MoonanComments to Author , Smita Ghosh, John E. Oeltmann, J. Steven Kammerer, Lauren S. Cowan, and Thomas R. Navin
Author affiliations: US Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 2

Demographic, behavioral, and clinical characteristics of persons involved in putative recent TB transmission events, by location, United States, 2005–2009*

US Census region, no. (%) persons,† and main characteristics Odds ratio (99% CI) Wald p value
West, 11,550 (31.3)
    Mycobacterium bovis TB 4.4 (2.2–8.8) <0.0001
    US-born 2.4 (4.3–4.7) <0.0001
    East-Asian phylogenetic lineage TB 2.4 (1.4–4.2) <0.0001
    Hispanic 2.3 (1.7–3.0) <0.0001
    Homeless‡ 1.9 (1.5–2.9) <0.0001
Midwest, 10,502 (28.5)
    US-born 2.5 (2.1–3.1) <0.0001
    Black, non-Hispanic 2.1 (1.7–2.6) <0.0001
    Substance abuser§ 1.4 (1.3–1.6) <0.0001
Northeast, 6,090 (16.5)
    Hispanic 2.1 (1.5–3.0) <0.0001
    East-Asian phylogenetic lineage TB 2.0 (1.1–3.6) 0.001
    US-born 1.6 (1.2–2.1) <0.0001
    Substance abuser§ 1.6 (1.2–2.1) <0.0001
South 8,718 (23.7)
    Black, non-Hispanic 3.6 (1.5–8.6) <0.0001
    US-born 3.2 (2.5–4.2) <0.0001
    Euro-American phylogenetic lineage TB 2.2 (1.1, 4.3) 0.004
    Substance abuser§ 1.5 (1.1–4.3) <0.0001
Total, 36,860

*TB, tuberculosis.
†Column percentage.
‡Self-reported homelessness within 12 mo preceding TB diagnosis.
§Self-reported excess alcohol consumption, injection drug use, or noninjection drug use within 12 mo preceding TB diagnosis.

Main Article

Page created: February 16, 2012
Page updated: February 16, 2012
Page reviewed: February 16, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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