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Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
SARS Transmission

Probable Secondary Infections in Households of SARS Patients in Hong Kong

Joseph T.F. Lau*Comments to Author , Mason Lau*, Jean H. Kim*, Eric Wong*, Hi-Yi Tsui*, Thomas Tsang†, and Tze Wai Wong‡
Author affiliations: *Chinese University of Hong Kong, Hong Kong Special Administrative Region, People’s Republic of China (SAR); †Department of Health, Hong Kong SAR; ‡Chinese University of Hong Kong, Department of Community and Family Medicine, Hong Kong SAR

Main Article

Table 1

Univariate association between various risk factors and Household Member Attack Rates (HMAR)

Risk factor % attack rate
Odds ratio (95% CI) Chi-square
p value
Case
Control
(n = 131) (n = 2,139)
Sexa




Male
46.6
48.3
1.00
0.701
Female
53.4
51.7
1.07 (0.75 to 1.53)

Age (y)b




18–30
46.6
46.9
1.00
0.287
31–40
15.3
15.3
1.17 (0.68 to 2.01)

41–50
16.2
16.3
1.04 (0.60 to 1.81)

51–60
10.9
10.7
1.58 (0.90 to 2.76)

>61
11.1
10.8
1.65 (0.95 to 2.86)

Type of Index Person (IP)




Hospital care workers
7.6
33.5
1.00
<0.001c
Amoy Gardens Block E residents
10.7
2.8
16.99 (7.23 to 39.90)

Amoy Gardens other Block residents
15.3
10.6
6.31 (2.91 to 13.67)

Other community members
66.4
53.2
5.48 (2.83 to 10.61)

Date of IP’s fever onsetd




Before March 25
51.9
34.2
1.00
<0.001
On or after March 25
48.1
65.8
0.48 (0.34 to 0.69)

Duration IP stayed home between fever onset and hospitalization (d)e




<2
31.3
51.0
1.00
<0.001
3–5
32.1
30.3
1.72 (1.11 to 2.68)

>6
36.6
18.8
3.18 (2.07 to 4.90)

IP visited by a family member during hospitalization?




No
73.3
87.9
1.00
<0.001
Yes
26.7
12.1
2.65 (1.76 to 3.98)

Mask use during hospital visits by a household memberf




Not visited by any household member
75.0
88.6
1.00
<0.0013
Visited, both with mask on
6.3
4.0
1.87 (0.88 to 3.96)

Visited, one with mask on
5.5
3.6
1.78 (0.80 to 3.96)

Visited, both without mask on
13.3
3.8
4.16 (2.37 to 7.30)

Whether caretaker of IP




No
64.9
82.0
1.00
<0.001
Yes
35.1
18.0
2.47 (1.70 to 3.60)

Whether shared room and bed with IPg




Never
59.7
81.3
1.00
<0.001
Sharing room
8.9
7.3
1.66 (0.86 to 3.19)

Sharing room and bed
31.5
11.4
3.74 (2.48 to 5.64)

Frequency of dining together with IPh




Never
37.0
60.2
1.00
<0.001
<5
21.8
18.7
1.90 (1.15 to 3.12)

5–10
14.3
9.7
2.40 (1.35 to 4.29)

>10
26.9
11.4
3.82 (2.38 to 6.15)

Frequency of close contact with IP (within 1 m)i




Never
22.5
48.4
1.00
<0.001
Seldom
15.0
14.7
2.19 (1.19 to 4.02)

Occasionally
24.2
16.4
3.17 (1.85 to 5.42)

Frequent
38.3
20.5
4.03 (2.47 to 6.56)

Frequency coughed at by IP (within 1 meter) j




Never
77.6
90.3
1.00
<0.0013
Seldom
6.5
4.2
1.81 (0.81 to 4.03)

Occasionally
10.3
2.8
4.29 (2.17 to 8.48)

Frequent 5.6 2.6 2.47 (1.03 to 5.90)

aInformation on 31 controls missing.
bInformation on 7 cases and 160 controls missing .
cChi-square test exact p value.
dInformation on 3 controls missing.
eInformation on 6 controls missing.
fInformation on 3 cases 18 controls missing.
gInformation on 7 cases and 24 controls missing.
hInformation on 12 cases and 51 controls missing.
iInformation on 13 cases and 37 controls missing.
jInformation on 24 cases and 98 controls missing.

Main Article

Page created: February 03, 2011
Page updated: February 03, 2011
Page reviewed: February 03, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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