Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 14, Number 12—December 2008
Letter

Human Case of Bartonella alsatica Lymphadenitis

Emmanouil Angelakis, Hubert Lepidi, Atbir Canel, Patrick Rispal, Françoise Perraudeau, Isabelle Barre, Jean-Marc Rolain, and Didier RaoultComments to Author 
Author affiliations: Université de la Méditerranée, Marseille, France (E. Angelakis, H. Lepidi, J.-M. Rolain, D. Raoult); Centre Hospitalier d’Agen, Agen, France (A. Canel, P. Rispal, F. Perraudeau, I. Barre)

Main Article

Appendix Figure

A) Western blotting analysis of lymph node specimen from the patient before 1) and after 2) cross-adsorption with Bartonella alsatica. Lane 1, B. quintana; lane 2, B. henselae; lane 3, B. elizabethae; lane 4, B. vinsonii subsp. berkhoffii; lane 5, B. alsatica. B) Characteristic histologic change in the lymph node with B. alsatica infection. Shown is an inflammatory granulomatous process with central microabscess surrounded by a ring of macrophages and rare giant cells (hematoxylin and eosin stain, original magnification x100). C) Bacteria (arrow) in an abscess formation mixed with necrotic debris (Warthin-Starry silver stain, original magnification x1,000). D) Immunohistochemical detection of B. alsatica (arrow) in lymph node pulp with an extracellular distribution (polyclonal antibody and hematoxylin counterstain, original magnification x400).

Appendix Figure. A) Western blotting analysis of lymph node specimen from the patient before 1) and after 2) cross-adsorption with Bartonella alsatica. Lane 1, B. quintana; lane 2, B. henselae; lane 3, B. elizabethae; lane 4, B. vinsonii subsp. berkhoffii; lane 5, B. alsatica. B) Characteristic histologic change in the lymph node with B. alsatica infection. Shown is an inflammatory granulomatous process with central microabscess surrounded by a ring of macrophages and rare giant cells (hematoxylin and eosin stain, original magnification x100). C) Bacteria (arrow) in an abscess formation mixed with necrotic debris (Warthin-Starry silver stain, original magnification x1,000). D) Immunohistochemical detection of B. alsatica (arrow) in lymph node pulp with an extracellular distribution (polyclonal antibody and hematoxylin counterstain, original magnification x400).

Main Article

Page created: July 22, 2010
Page updated: July 22, 2010
Page reviewed: July 22, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external