Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 16, Number 6—June 2010
Dispatch

Variations in Human Herpesvirus Type 8 Seroprevalence in Native Americans, South America

Vanda A.U.F. Souza, Francisco M. Salzano, Maria Luiza Petzl-Erler, Maria Claudia Nascimento, Philippe Mayaud, Jaila Dias Borges, and Claudio S. PannutiComments to Author 
Author affiliations: Universidade de São Paulo, São Paulo, Brazil (V.A.U.F. Souza, C.S. Pannuti, M.C. Nascimento, J.D. Borges); Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil (F.M. Salzano); Universidade Federal do Paraná, Curitiba, Brazil (M.L. Petzl-Erler); London School of Hygiene and Tropical Medicine, London, UK (M.C. Nascimento, P. Mayaud).

Main Article

Table 2

Previous human herpesvirus type 8 seroprevalence studies in Amazonian Native American populations*

Population† No. positive/no. tested (%) HHV-8 assay used‡ Reference
Wai Wai, Brazil 275/339 (81) IFA-LANA, IFA-Lytic (5)
Zoé, Brazil 18/49 (37) EIA-ORF59/0RF65/K8.1 (4)
Emerillon, French Guiana 12/78 (15) IFA-Lytic (ABI test) (6)
Palikur, French Guiana 22/167 (13) IFA-Lytic (ABI test) (6)
Wayana, French Guiana 41/144 (28) IFA-Lytic (ABI test) (6)
Wayampi, French Guiana 93/302 (31) IFA-Lytic (ABI test) (6)
Wayampi, Brazil 85/123 (69) IFA-LANA, IFA-Lytic (3)
Wayampi, Brazil 28/33 (85) IFA-LANA, EIA w-virus (2)
Tiriyó, Brazil 381/664 (57) IFA-LANA, IFA-Lytic (3)
Tiriyó, Brazil 30/35 (86) IFA-LANA, EIA w-virus (2)
Tiriyó, Brazil 24/56 (43) EIA-ORF59/0RF65/K8.1 (4)
Huaroni, Ecuador 38/38 (100) IFA-LANA, EIA-K8.1, EIA-ORF73 (7)
Siona, Ecuador 10/41 (24) IFA-LANA, EIA-K8.1, EIA-ORF73 (7)
Apalaí, Brazil 8/44 (18) IFA-LANA, EIA w-virus (2)
Arara-Laranja, Brazil 18/92 (20) EIA-ORF59/0RF65/K8.1 (4)
Arara-Laranjal, Brazil 0/11 (0) IFA-LANA, EIA w-virus (2)
Kararao, Brazil 6/24 (25) EIA-ORF59/0RF65/K8.1 (4)
Asurini-Koatinemo, Brazil 7/10 (70) IFA-LANA, EIA w-virus (2)
Munduruku, Brazil 36/40 (90) IFA-LANA, EIA w-virus (2)
Araweté, Brazil 12/17 (71) IFA-LANA, EIA w-virus (2)
Parakanã, Brazil 27/30 (90) IFA-LANA, EIA w-virus (2)
Xikrin, Brazil 20/34 (59) IFA-LANA, EIA w-virus (2)
Karitiana, Brazil 12/25 (48) IFA-LANA, EIA w-virus (2)
Suruí, Brazil 15/17 (88) IFA-LANA, EIA w-virus (2)
Mekranoti, Brazil 34/52 (65) IFA-LANA, EIA w-virus (2)
Cinta Larga, Brazil 1/14 (7) IFA-LANA, EIA w-virus (2)

*ABI, Advanced Biotechnologies Inc (Columbia, MD, USA); EIA, enzyme immunoassay; IFA, immunofluorescence assay; LANA, latency-associated nuclear antigen; ORF, open reading frame; w-virus, whole-virus assay.
†Listed in north-south gradient (Figure).
‡Only series with >10 persons are presented.

Main Article

References
  1. Boshoff  C, Weiss  RA. Epidemiology and pathogenesis of Kaposi’s sarcoma–associated herpesvirus. Philos Trans R Soc Lond B Biol Sci. 2001;356:51734. DOIPubMedGoogle Scholar
  2. Biggar  RJ, Whitby  D, Marshall  V, Linhares  AC, Black  F. Human herpesvirus 8 in Brazilian Amerindians: a hyperendemic population with a new subtype. J Infect Dis. 2000;181:15628. DOIPubMedGoogle Scholar
  3. Cunha  AM, Caterino-de-Araujo  A, Costa  SC, Santos-Fortuna  E, Boa-Sorte  NC, Goncalves  MS, Increasing seroprevalence of human herpesvirus 8 (HHV-8) with age confirms HHV-8 endemicity in Amazon Amerindians from Brazil. J Gen Virol. 2005;86:24337. DOIPubMedGoogle Scholar
  4. Ishak Mde  O, Martins  RN, Machado  PRL, Souza  LBB, Machado  LFA, Azevedo  VN, High diversity of HHV-8 molecular subtypes in the Amazon region of Brazil: evidence of an ancient human infection. J Med Virol. 2007;79:153744. DOIPubMedGoogle Scholar
  5. de Souza  VA, Sumita  LM, Nascimento  MC, Oliveira  J, Mascheretti  M, Quiroga  M, Human herpesvirus-8 infection and oral shedding in Amerindian and non-Amerindian populations in the Brazilian Amazon region. J Infect Dis. 2007;196:84452. DOIPubMedGoogle Scholar
  6. Kazanji  M, Dussart  P, Duprez  R, Tortevoye  P, Pouliquen  J-F, Vandekerkhove  J, Serological and molecular evidence that human herpesvirus 8 is endemic among Amerindians in French Guiana. J Infect Dis. 2005;192:15259. DOIPubMedGoogle Scholar
  7. Whitby  D, Marshall  VA, Bagni  RK, Wang  CD, Gamache  CJ, Guzman  JR, Genotypic characterization of Kaposi's sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations. J Gen Virol. 2004;85:15563. DOIPubMedGoogle Scholar
  8. Plancoulaine  S, Abel  L, van Beveren  M, Tregouet  DA, Joubert  M, Tortevoye  P, Human herpesvirus 8 transmission from mother to child and between siblings in an endemic population. Lancet. 2000;356:10625. DOIPubMedGoogle Scholar
  9. Dedicoat  M, Newton  R, Alkharsah  KR, Sheldon  J, Szabados  I, Ndlovu  B, Mother-to-child transmission of human herpesvirus-8 in South Africa. J Infect Dis. 2004;190:106875. DOIPubMedGoogle Scholar
  10. Salzano  FM, Gershowitz  H, Junqueira  PC, Woodal  JP, Black  FL, Hierholzer  W. Blood groups and H-Lea salivary secretion of Brazilian Cayapo Indians. Am J Phys Anthropol. 1972;36:41725. DOIPubMedGoogle Scholar
  11. Salzano  FM, Neel  JV, Gershowitz  H, Migliazza  EC. Intra and intertribal genetic variation within a linguistic group: the Ge-speaking Indians of Brazil. Am J Phys Anthropol. 1977;47:33747. DOIPubMedGoogle Scholar
  12. Tsuneto  LT, Probst  CM, Hutz  MH, Salzano  FM, Rodriguez-Delfin  LA, Zago  MA, HLA class II diversity in seven Amerindian populations. Clues about the origins of the Aché. Tissue Antigens. 2003;62:51226. DOIPubMedGoogle Scholar
  13. Dornelles  CL, Battilana  J, Fagundes  NJR, Freitas  LB, Bonatto  SL, Salzano  FM. Mitochondrial DNA and Alu insertions in a genetically peculiar population: the Ayoreo Indians of Bolivia and Paraguay. Am J Hum Biol. 2004;16:47988. DOIPubMedGoogle Scholar
  14. Nascimento  MC, Souza  VA, Sumita  LM, Freire  W, Munoz  F, Kim  J, Comparative study of Kaposi’s sarcoma-associated herpesvirus serological assays using clinically and serologically defined reference standards and latent class analysis. J Clin Microbiol. 2007;45:71520. DOIPubMedGoogle Scholar
  15. Marrero  AR, Silva-Junior  WA, Bravi  CM, Hutz  MH, Petzl-Erler  ML, Ruiz-Linares  A, Demographic and evolutionary trajectories of the Guarani and Kaingang natives of Brazil. Am J Phys Anthropol. 2007;132:30110. DOIPubMedGoogle Scholar

Main Article

Page created: February 07, 2011
Page updated: February 07, 2011
Page reviewed: February 07, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external