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Volume 11, Number 5—May 2005

Toscana Virus and Acute Meningitis, France

Christophe N. Peyrefitte*Comments to Author , Ivan Devetakov†, Boris Pastorino*, Laurent Villeneuve†, Mael Bessaud*, Philippe Stolidi†, Jerome Depaquit‡, Laurence Segura†, Patrick Gravier*, Fabienne Tock*, Francoise Durand†, Jean-Paul Vagneur†, Hugues J. Tolou*, and Marc Grandadam*
Author affiliations: *Laboratoire Associé au Centre National de Référence des Arbovirus, Marseille, France; †Centre Hospitalier Edmond Garcin, Aubagne, France; ‡Faculté de Pharmacie, Reims, France

Main Article


Arbovirus antibody investigation of samples*

Viral antigens CSF†
Serum 1†
Serum 2‡
IgM§ IgG¶ IgM IgG IgM IgG
Dengue 1.16 1.08 1.06 1.06 1.32 0.94
West Nile 1.06 0.92 0.96 1.03 1.27 1.29
Toscana 2.84 0.97 2.50 0.94 48.72 3.48
Sandfly fever Sicilian 0.98 0.96 0.96 0.96 1.20 0.86
Tickborne encephalitis (Langat) 0.88 1.15 1.09 0.96 1.22 0.74
Tahyna 0.98 0.94 0.96 1.00 1.20 1.17

*CSF, cerebrospinal fluid; Ig, immunoglobulin; MAC-ELISA, immunoglobulin M antigen capture enzyme-linked immunosorbent assay. Values are the ratio OD(viral antigen)/OD(control antigen). Samples were considered positive if the ratio is over 3. Bold values indicate positive results.
†CSF and serum obtained at the onset of the disease.
‡Serum obtained 30 days after the onset of the disease. §MAC-ELISA.

Main Article

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Page updated: April 24, 2012
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