Marie-Louise Vachon*†, Natasha Dionne*†, Éric Leblanc*†, Danielle Moisan‡, Michel G. Bergeron*†, and Guy Boivin*†
Figure 2. Phylogenetic analysis based on fusion (F) gene nucleotide sequences from clinical and reference human parainfluenza virus (HPIV) strains. The tree was built by using distance method and the neighbor-joining algorithm with Kimura 2 parameters. The topologic accuracy of the tree was evaluated by using 500 bootstrap replicates. Strains isolated at the Research Center in Infectious Diseases (Quebec, Canada) are indicated by a specific identification number (ccri) followed by the patient number in parentheses. Public sequences for HPIV-4A (GenBank accession no. d49821) and HPIV-4B (GenBank accession no. d49822) strains are also indicated in the tree.