Volume 12, Number 3—March 2006
Chemoprophylaxis and Malaria Death Rates
|Risk factor||Odds ratio||95% confidence interval||p value|
|Chemoprophylaxis, total (n = 3,752)|
|Chemoprophylaxis, comparison of regimens (n = 3,752)||0.047|
|None (n = 2,171)||1|
|Chloroquine alone (n = 485)||1.372||0.824-2.285||0.225|
|Proguanil alone (n = 59)||0.550||0.075-4.030||0.556|
|Mefloquine alone (n = 322)||0.503||0.201-1.258||0.142|
|Chloroquine plus proguanil (n = 459)||0.280||0.102-0.773||0.014|
|Other (n = 256)*||0.765||0.328-1.784||0.536|
|Compliance of chemoprophylaxis (n = 3717)||0.293†|
|Chemoprophylaxis with incomplete or unknown compliance||0.829||0.535-1.284||0.401|
|Age (n = 3,844)|
|Continuously (by year)||1.055||1.040-1.070||<0.001|
|Sex (n = 3,901)|
|Country of infection in Africa (n = 3,832)|
|Reporting year (n = 3,935)||0.004†|
*235 were combinations of drugs that are not officially recommended regimens, 15 were doxycycline alone, and 6 were atovaquone/proguanil.
†Overall p value for the categoric variable.
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