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Volume 17, Number 7—July 2011

Rickettsia parkeri Rickettsiosis, Argentina

Yamila RomerComments to Author , Alfredo C. Seijo, Favio Crudo, William L. Nicholson, Andrea Varela-Stokes, R. Ryan Lash, and Christopher D. Paddock
Author affiliations: Author affiliations: Hospital F.J. Muñiz, Buenos Aires, Argentina (Y. Romer, A.C. Seijo, F. Crudo); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (W.L. Nicholson, C.D. Paddock); Mississippi State University, Mississippi State, Mississippi, USA (A. Varela-Stokes); The University of Georgia, Athens, Georgia, USA (R.R. Lash)

Main Article


Comparison of selected clinical characteristics reported for suspected and confirmed cases of Rickettsia parkeri rickettsiosis in patients from Argentina and the United States, 2004–2009*

Clinical characteristic % Argentina patients, n = 10 % United States patients, n = 15
Fever 100 100
Inoculation eschar
Any type 100 87
Macules or papules 90 87
Vesicles or pustules 50 40
Petechiae 20 13
On palms or soles
Headache 90 80
Myalgias 70 80
Sore throat 30 NR†
Injected conjunctivae 10 NR
Lymphadenopathy 10 27
Diarrhea 10 0
Nausea or vomiting
Hospitalization 0 33
Death 0 0

*See (3,5,11).
†NR, not reported.

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  1. Paddock  CD, Sumner  JW, Comer  JA, Zaki  SR, Goldsmith  CS, Goddard  J, Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United States. Clin Infect Dis. 2004;38:80511. DOIPubMedGoogle Scholar
  2. Whitman  TJ, Richards  AL, Paddock  CD, Tamminga  CL, Sniezek  PJ, Jiang  J, Rickettsia parkeri infection after tick bite, Virginia. Emerg Infect Dis. 2007;13:3346. DOIPubMedGoogle Scholar
  3. Cragun  WC, Bartlett  BL, Ellis  MW, Hoover  AZ, Tyring  SK, Mendoza  N, The expanding spectrum of eschar-associated rickettsioses in the United States. Arch Dermatol. 2010;146:6418. DOIPubMedGoogle Scholar
  4. Sumner  JW, Durden  LD, Goddard  J, Stromdahl  EY, Clark  KL, Reeves  WK, Gulf Coast ticks (Amblyomma maculatum) and Rickettsia parkeri, United States. Emerg Infect Dis. 2007;13:7513.PubMedGoogle Scholar
  5. Seijo  A, Picollo  M, Nicholson  W, Paddock  C. Fiebre manchada por rickettsias en el Delta del Parana: una enfermedad emergente. Medicina (B Aires). 2007;67:7236.PubMedGoogle Scholar
  6. Conti-Díaz  IA. Rickettsiosis por Rickettsia conorii (fiebre botonosa del Mediterráneo fiebre de Marsella): estado actual en Uruguay. Rev Med Uruguay. 2001;17:11924.
  7. Conti-Díaz  IA, Morales Filho  J, Pacheco  RC, Labruna  MB. Serological evidence of Rickettsia parkeri as the eiological agent of rickettsiosis in Uruguay. Rev Inst Med Trop Sao Paulo. 2009;51:3379. DOIPubMedGoogle Scholar
  8. Venzal  JM, Portillo  A, Estrada-Peña  A, Castro  O, Cabrera  PA, Oteo  JA. Rickettsia parkeri in Amblyomma triste from Uruguay. Emerg Infect Dis. 2004;10:14935.PubMedGoogle Scholar
  9. Silveira  I, Pacheco  RC, Szabó  MP, Ramos  HG, Labruna  MB. Rickettsia parkeri in Brazil. Emerg Infect Dis. 2007;13:11113.PubMedGoogle Scholar
  10. Nava  S, Elshewany  Y, Eremeeva  ME, Sumner  JW, Mastropaolo  M, Paddock  CD. Rickettsia parkeri in Argentina. Emerg Infect Dis. 2008;14:18947. DOIPubMedGoogle Scholar
  11. Paddock  CD, Finley  RW, Wright  CS, Robinson  HN, Schrodt  BJ, Lane  CC, Rickettsia parkeri rickettsiosis and its clinical distinction from Rocky Mountain spotted fever. Clin Infect Dis. 2008;47:118896. DOIPubMedGoogle Scholar
  12. Roux  V, Raoult  D. Phylogenetic analysis of members of the genus Rickettsia using the gene encoding the outer-membrane protein rOmpB (ompB). Int J Syst Evol Microbiol. 2000;50:144955. DOIPubMedGoogle Scholar
  13. Labruna  MB, Whitworth  T, Horta  MC, Bouyer  DH, McBride  JW, Pinter  A, Rickettsia species infecting Amblyomma cooperi ticks from an area in the State of São Paulo, Brazil, where Brazilian spotted fever is endemic. J Clin Microbiol. 2004;42:908. DOIPubMedGoogle Scholar
  14. Larkin  MA, Blackshields  G, Brown  NP, Chenna  R, McGettigan  PA, McWilliam  H, Clustal W and Clustal X version 2. Bioinformatics. 2007;23:29478. DOIPubMedGoogle Scholar
  15. Zavala-Velazquez  JE, Yu  X-J, Walker  DH. Unrecognized spotted fever group rickettsiosis masquerading as dengue fever in Mexico. Am J Trop Med Hyg. 1996;55:1579.PubMedGoogle Scholar
  16. Hidalgo  M, Orejuela  L, Fuya  P, Carrillo  P, Hernandez  J, Parra  E, Rocky Mountain spotted fever, Colombia. Emerg Infect Dis. 2007;13:105860.PubMedGoogle Scholar
  17. Raoult  D, La Scola  B, Enea  M, Fournier  PE, Roux  V, Fenollar  F, A flea-associated Rickettsia pathogenic for humans. Emerg Infect Dis. 2001;7:7381. DOIPubMedGoogle Scholar
  18. Garcia-Garcia  JC, Portillo  A, Núñez  MJ, Santibáñez  S, Castro  B, Oteo  JA. Case report: a patient from Argentina infected with Rickettsia massiliae. Am J Trop Med Hyg. 2010;82:6912. DOIPubMedGoogle Scholar
  19. Spolidorio  MG, Labruna  MB, Mantovani  E, Brandão  PE, Richtzenhain  LJ, Yoshinari  NH. Novel spotted fever rickettsiosis, Brazil. Emerg Infect Dis. 2010;16:5213. DOIPubMedGoogle Scholar
  20. Silva  N, Eremeeva  ME, Rozental  T, Ribeiro  GS, Paddock  CD, Ramos  EA, Eschar-asociated spotted fever rickettsiosis, Bahia, Brazil. [PMID: 21291605]. Emerg Infect Dis. 2011;17:2736.
  21. Ripoll  CM, Remondegui  CE, Ordonez  G, Arazamendi  R, Fusaro  H, Hyman  MJ, Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina. Am J Trop Med Hyg. 1999;61:3504.PubMedGoogle Scholar
  22. Paddock  CD, Fernandez  S, Echenique  GA, Sumner  JW, Reeves  WK, Zaki  SR, Rocky Mountain spotted fever in Argentina. Am J Trop Med Hyg. 2008;78:68792.PubMedGoogle Scholar
  23. Violante  RA, Cavallotto  JL, Kandus  P. Río de la Plata y Delta del Paraná. In: Ardolino A, Lema H, editors. Sitios de interés geológico de la República Argentina. Servicio geológico minero argentino. Buenos Aires Instituto de geología y recursos minerales. Anales no. 46; 2008. p. 461–75.

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Page created: August 18, 2011
Page updated: August 18, 2011
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