Volume 2, Number 2—April 1996
News and Notes
BSE Meeting at CDC
The recent report of a new variant of Creutzfeldt-Jakob disease (V-CJD) in Great Britain and the possible link between the disease and bovine spongiform encephalopathy (BSE) has raised a number of health and safety concerns (1,2). On April 8, 1996, CDC organized a meeting of U.S. agency representatives to review information about the report of U.K. cases and about efforts to identify the existence of BSE and V-CJD in the United States. The meeting covered the scientific evidence for the report of V-CJD; recommendations from a meeting of international experts organized by the World Health Organization on April 2-3; and the current and proposed activities of U.S. agencies with regard to BSE and V-CJD.
Among the observations made during the meeting were the following:
There is no evidence from U.S. surveillance activities or from scientific studies to indicate that BSE exists in the United States.
Active surveillance for BSE is conducted by the U.S. Department of Agriculture (USDA). All cattle presented for slaughter in the United States are observed for signs of central nervous system (CNS) disorders. Livestock showing CNS signs are condemned and not allowed to enter the slaughter plant or to become part of the human food supply. Since 1990, laboratory testing of nearly 2,800 brain specimens from cattle with CNS signs has shown no evidence of BSE.
No U.K. cattle or ruminant-based feed has been imported into the United States since July 1989, when USDA banned the importation of cattle and cattle products from the United Kingdom. U.K. cattle imported before the ban will be destroyed as a precaution to ensure that these animals do not enter the food chain (human or animal).
The Food and Drug Administration plans to issue a ban on ruminant-to-ruminant feeding in the United States.
Additional research is needed on the characterization of the causative agent of BSE and on the epidemiology, rapid laboratory diagnosis, and pathogenesis of BSE and CJD.
The Centers for Disease Control and Prevention (CDC) monitors the occurrence of CJD in the United States through surveillance and special epidemiologic studies (3). On the basis of mortality surveillance from 1979 to 1993, the annual incidence of CJD remained stable at approximately one case per million persons. In the United Kingdom, five of eight patients who died of V-CJD since May 1995 were younger than 30 years of age; by comparison, in the United States, CJD deaths among persons younger than 30 years are extremely rare (fewer than 5 per billion per year). CDC’s efforts will be expanded to include active surveillance studies at four Emerging Infections Program sites (Connecticut, Minnesota, Oregon, and the San Francisco area) and in Atlanta to provide more up-to-date information on the occurrence of CJD and to verify the absence or presence of V-CJD.
Future cooperative efforts among U.S. agencies, industry, and other interested parties in response to the report of V-CJD are planned. The report of the April 8 meeting at CDC is available on the CDC NCID Web site at http://www.cdc.gov/ncidod/diseases/cjd/cjd.htm.
- Will RG, Ironside JW, Zeibler M, A new variant of Creutzfeldt-Jakob disease in the UK. Lancet. 1996;347:921–5. DOIPubMedGoogle Scholar
- CDC. World Health Organization consultation on public health issues related to bovine spongiform encephalopathy and the emergence of a new variant of Creutzfeldt-Jakob disease. MMWR. 1996;45:295–6, 303.PubMedGoogle Scholar
- Holman RC, Khan AS, Kent J, Strine TW, Schonberger LB. Epidemiology of Creutzfeldt-Jakob disease in the United States, 1979-1990: analysis of national mortality data. Neuroepidemiology. 1995;14:174–81. DOIPubMedGoogle Scholar
Table of Contents – Volume 2, Number 2—April 1996
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