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Volume 21, Number 11—November 2015
Dispatch

Use of Whole-Genome Sequencing to Link Burkholderia pseudomallei from Air Sampling to Mediastinal Melioidosis, Australia

Bart J. CurrieComments to Author , Erin P. Price, Mark Mayo, Mirjam Kaestli, Vanessa Theobald, Ian Harrington, Glenda Harrington, and Derek Sarovich
Author affiliations: Royal Darwin Hospital, Darwin, Northern Territory, Australia (B.J. Currie); Menzies School of Health Research, Casuarina, Northern Territory (B.J. Currie, E.P. Price, M. Mayo, M. Kaestli, V. Theobald, I. Harrington, G. Harrington, D.S. Sarovich)

Main Article

Figure 2

Whole-genome core orthologous single nucleotide polymorphism (SNP) phylogeny of sequence type 562 B. pseudomallei isolates from a patient with melioidosis and from environmental sampling at the patient’s residence, Darwin, Northern Territory, Australia. MSHR4515 (MLST database identifier, http://bpseudomallei.mlst.net/) was a blood culture isolate from the index patient, identified as patient (P) 692 (P692, arrow). Analysis of isolates from 13 other patients with sequence type 562 are also shown

Figure 2. Whole-genome core orthologous single-nucleotide polymorphism (SNP) phylogeny of sequence type 562 Burkholderia pseudomallei isolates from a patient with melioidosis and from environmental sampling at the patient’s residence, Darwin, Northern Territory, Australia. MSHR4515 (MLST database identifier, http://bpseudomallei.mlst.net/) was a blood culture isolate from the index patient, identified as patient (P) 692 (P692, arrow). Analysis of isolates from 13 other patients with sequence type 562 are also shown (identifiers begin with P). Comparison of data for NPs and for multilocus variable-number tandem-repeat analysis of 4 loci (MLVA-4) types (shown in parentheses) supports the hypothesis that P692 was infected from environmental B. pseudomallei at his residence. Consistency index = 1.

Main Article

Page created: October 19, 2015
Page updated: October 19, 2015
Page reviewed: October 19, 2015
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