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Volume 21, Number 11—November 2015
Research

Role of Maternal Antibodies in Infants with Severe Diseases Related to Human Parechovirus Type 31

Yuta Aizawa, Kanako Watanabe, Tomohiro Oishi, Harunobu Hirano, Isao Hasegawa, and Akihiko SaitohComments to Author 
Author affiliations: Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan (Y. Aizawa, T. Oishi, A. Saitoh); Niigata University Graduate School of Health Sciences, Niigata (K. Watanabe); Saiseikai Niigata Daini Hospital, Niigata (H. Hirano, I. Hasegawa); University of California San Diego School of Medicine, San Diego, California, USA (A. Saitoh)

Main Article

Table 2

NATs to HPeV types 1, 3, and 6 in intravenous immunoglobulin preparations commercially available in Japan*

Preparation Country† Year obtained IVIG treatment NATs
HPeV1 HPeV3 HPeV6
Batch 1 Japan 2010, 2011 PEG 1:1,024 1:512 1:2,048
Batch 2 Japan 2010 Freeze-dried PEG 1:1,024 1:512 1:1,024
Batch 3-1 Japan 2011 Sulfonation 1:1,024 1:512 1:2,048
Batch 3-2 Japan 2011, 2012 Sulfonation 1:1,024 1:1,024 1:2,048
Batch 4 United States 2012 Ion-exchange resin 1:1,024 1:512 1:2,048
Batch 5 Germany 2012 pH4 1:2,048 1:512 1:2,048

*HPeV1, human parechovirus type 1; IVIG, intravenous immunoglobulin; NATs, neutralizing antibody titers; PEG, polyethylene glycol.
†Country where IVIG was obtained.

Main Article

1Presented in part at IDWeek, October 8–12, 2014, Philadelphia, Pennsylvania, USA.

Page created: October 16, 2015
Page updated: October 16, 2015
Page reviewed: October 16, 2015
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