Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 21, Number 5—May 2015

Pathologic Changes in Wild Birds Infected with Highly Pathogenic Avian Influenza A(H5N8) Viruses, South Korea, 2014

Hye-Ryoung Kim, Yong-Kuk Kwon, Il Jang, Youn-Jeong Lee, Hyun-Mi Kang, Eun-Kyoung Lee, Byung-Min Song, Hee-Soo Lee, Yi-Seok Joo, Kyung-Hyun Lee, Hyun-Kyoung Lee, Kang-Hyun Baek, and You-Chan BaeComments to Author 
Author affiliations: Animal and Plant Quarantine Agency, Anyang, South Korea

Main Article

Table 2

Wild birds infected with highly pathogenic avian influenza A(H5N8) virus, South Korea, 2014*

No. birds, n = 167
Gross lesions
Infected organs
Other cause of death
Baikal teal (Anas formosa) 122 Donglim Reservoir Jan 17–22 Y T, C, K, L, Lu, P None
1 Jeonbuk Jan 21 Y P None
5 Geumgang River Jan 22, 27 Y T, C, K, Lu, P None
20 Chungnam Jan 23 Y T, K, P, H Monocrotophos poisoning
Bean goose (Anser fabalis) 9 Donglim Reservoir Jan 19–21 N T (K) Monocrotophos poisoning (3)
1 Incheon Feb 1 Y UK None
1 Gyeonggi Mar 9 Y T, C, P None
Mallard (Anas platyrhychos) 1 Jeonnam Jan 27 N UK Peritonitis
1 Jeonnam Jan 29 N UK Gunshot, parasite infection
White-fronted goose (Anser albifrons) 1 Gyeonggi Jan 28 N UK None
Whooper swan (Cygnus cygnus)
Feb 6
Renal failure
Other (not Anatidae)
Coot (Fulica atra) 1 Donglim Reservoir Jan 22 None I, K Postmortem change
Little grebe (Podicdeps ruficollis) 2 Gyeonggi Feb 27 None T, C, K Postmortem change
Great egret (Egretta alba alba) 1 Jeonbuk Mar 8 N UK Peritonitis

*C, cecal tonsil; H, heart; I, intestine, K, kidney; L, liver; Lu, lung; N, no; T, trachea P, pancreas; UK, unknown (pooled trachea, cecal tonsil, and kidney); Y, yes.

Main Article

  1. Swayne  DE, Suarez  D. Highly pathogenic avian influenza. Rev Sci Tech. 2000;19:46382 .PubMedGoogle Scholar
  2. Chen  H, Smith  G, Zhang  S, Qin  K, Wang  J, Li  K, Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature. 2005;436:1912. DOIPubMedGoogle Scholar
  3. Perkins  LE, Swayne  DE. Varied pathogenicity of a Hong Kong–origin H5N1 avian influenza virus in four passerine species and budgerigars. Vet Pathol. 2003;40:1424. DOIPubMedGoogle Scholar
  4. Teifke  JP, Klopfleisch  R, Globig  A, Starick  E, Hoffmann  B, Wolf  P, Pathology of natural infections by H5N1 highly pathogenic avian influenza virus in mute (Cygnus olor) and whooper (Cygnus cygnus) swans. Vet Pathol. 2007;44:13743. DOIPubMedGoogle Scholar
  5. Kwon  YK, Thomas  C, Swayne  DE. Variability in pathobiology of South Korean H5N1 high-pathogenicity avian influenza virus infection for 5 species of migratory waterfowl. Vet Pathol. 2010;47:495506. DOIPubMedGoogle Scholar
  6. Lee  Y-J, Choi  Y-K, Kim  Y-J, Song  M-S, Jeong  O-M, Lee  E-K, Highly pathogenic avian influenza virus (H5N1) in domestic poultry and relationship with migratory birds, South Korea. Emerg Infect Dis. 2008;14:487. DOIPubMedGoogle Scholar
  7. Kim  H-R, Park  C-K, Lee  Y-J, Woo  G-H, Lee  K-K, Oem  J-K, An outbreak of highly pathogenic H5N1 avian influenza in Korea, 2008. Vet Microbiol. 2010;141:3626. DOIPubMedGoogle Scholar
  8. Kim  H-R, Lee  Y-J, Park  C-K, Oem  J-K, Lee  O-S, Kang  H-M, Highly pathogenic avian influenza (H5N1) outbreaks in wild birds and poultry, South Korea. Emerg Infect Dis. 2012;18:4803. DOIPubMedGoogle Scholar
  9. Lee  C-W, Suarez  DL, Tumpey  TM, Sung  H-W, Kwon  Y-K, Lee  Y-J, Characterization of highly pathogenic H5N1 avian influenza A viruses isolated from South Korea. J Virol. 2005;79:3692702. DOIPubMedGoogle Scholar
  10. Jeong  J, Kang  H-M, Lee  E-K, Song  B-M, Kwon  Y-K, Kim  H-R, Highly pathogenic avian influenza virus (H5N8) in domestic poultry and its relationship with migratory birds in South Korea during 2014. Vet Microbiol. 2014;173:24957. DOIPubMedGoogle Scholar
  11. Lee  Y-J, Kang  H-M, Lee  E-K, Song  B-M, Jeong  J, Kwon  Y-K, Novel reassortant influenza A (H5N8) viruses, South Korea, 2014. Emerg Infect Dis. 2014;20:10879. DOIPubMedGoogle Scholar
  12. Ko  KY, Shin  JY, Kim  D-G, Kim  M, Son  S-W. Determination of organophosphorus pesticides in stomach contents of postmortem animals by QuEChERS and gas chromatography. J Anal Toxicol. 2014;38:66771 . DOIPubMedGoogle Scholar
  13. Perkins  LE, Swayne  DE. Pathobiology of A/chicken/Hong Kong/220/97 (H5N1) avian influenza virus in seven gallinaceous species. Vet Pathol. 2001;38:14964. DOIPubMedGoogle Scholar
  14. Keawcharoen  J, Van Riel  D, van Amerongen  G, Bestebroer  T, Beyer  WE, Van Lavieren  R, Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1). Emerg Infect Dis. 2008;14:600. DOIPubMedGoogle Scholar
  15. Kalthoff  D, Breithaupt  A, Teifke  JP, Globig  A, Harder  T, Mettenleiter  TC, Pathogenicity of highly pathogenic avian influenza virus (H5N1) in adult mute swans. Emerg Infect Dis. 2008;14:1267. DOIPubMedGoogle Scholar
  16. Brown  JD, Stallknecht  DE, Valeika  S, Swayne  DE. Susceptibility of wood ducks to H5N1 highly pathogenic avian influenza virus. J Wildl Dis. 2007;43:6607. DOIPubMedGoogle Scholar
  17. Gaidet  N, Cattoli  G, Hammoumi  S, Newman  SH, Hagemeijer  W, Takekawa  JY, Evidence of infection by H5N2 highly pathogenic avian influenza viruses in healthy wild waterfowl. PLoS Pathog. 2008;4:e1000127. DOIPubMedGoogle Scholar
  18. Kim  H-R, Kim  B-S, Bae  Y-C, Moon  O-K, Oem  J-K, Kang  H-M, H5N1 subtype highly pathogenic avian influenza virus isolated from healthy mallard captured in South Korea. Vet Microbiol. 2011;151:3869. DOIPubMedGoogle Scholar
  19. Swayne  DE, Alexander  DJ. Confirmation of nephrotropism and nephropathogenicity of three low‐pathogenic chicken‐origin influenza viruses for chickens. Avian Pathol. 1994;23:34552. DOIPubMedGoogle Scholar
  20. Bonfante  F, Fusaro  A, Zanardello  C, Patrono  LV, De Nardi  R, Maniero  S, Lethal nephrotropism of an H10N1 avian influenza virus stands out as an atypical pathotype. Vet Microbiol. 2014;173:189200. DOIPubMedGoogle Scholar
  21. Cardona  CJ, Xing  Z, Sandrock  CE, Davis  CE. Avian influenza in birds and mammals. Comp Immunol Microbiol Infect Dis. 2009;32:25573. DOIPubMedGoogle Scholar
  22. Chan  PK. Outbreak of avian influenza A (H5N1) virus infection in Hong Kong in 1997. Clin Infect Dis. 2002;34(Suppl 2):S5864. DOIPubMedGoogle Scholar
  23. Swayne  DE, Pantin-Jackwood  M. Pathobiology of avian influenza virus infections in birds and mammals. In: Swayne DE, editor. Avian influenza. Hoboken (NJ): John Wiley and Sons; 2008. p. 87–122.

Main Article

Page created: April 18, 2015
Page updated: April 18, 2015
Page reviewed: April 18, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.