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Volume 21, Number 8—August 2015
Research

Response Strategies against Meningitis Epidemics after Elimination of Serogroup A Meningococci, Niger

Halima Boubacar MaïnassaraComments to Author , Juliette Paireau, Issa Idi, Jean-Paul Moulia Pelat, Odile Ouwe Missi Oukem-Boyer, Arnaud Fontanet, and Judith E. Mueller
Author affiliations: Université Pierre et Marie Curie, Paris (H.B. Maïnassara, J. Paireau); Institut Pasteur, Paris, France (H.B. Maïnassara, J. Paireau, A. Fontanet, J.E. Mueller); Centre de Recherche Médicale et Sanitaire, Niamey, Niger (H.B. Maïnassara, I. Idi, J.-P.M. Pelat, O.O.M. Oukem-Boyer); Chaire Santé et Développement, Paris (A. Fontanet); Ecole des Hautes Études en Santé Publique, Rennes, France (J.E. Mueller)

Main Article

Table 2

Comparison of estimated vaccine-preventable meningitis cases using different strategies of surveillance and meningococcal vaccine response before introduction of PsA-TT, Tahoua, Tillabery, and Dosso regions, Niger, 2002–September 2011

Strategy, surveillance–vaccination Threshold* Total no. epidemic signals Population affected by signal Vaccine doses in persons 1–29 y
 Vaccine preventable cases
No.
 Per 100,000 doses
Total Median Total Median Total Median Range
Health area–health area 7 844 14,742,136 10,909,180 10,051 2,282 0.64 20.92 5.18 0–595.34
10 679 11,567,626 8,560,043 10,081 1,924 0.64 22.48 5.41 0–595.34
15 469 7,849,057 5,808,302 9,587 1,332 0.64 22.93 5.59 0–482.10
20 358 5,791,671 5,791,671 9,307 1,087 0.64 25.36 6.14 0–482.10
30
 235
 3,719,950
 3,719,950
 8,919
 717
 0.64
26.05
 8.25
 0–482.10
Health area–district 7 844 47,090,036 34,846,626 250,877 3,739 4.64 10.73 3.42 0–70.20
10 679 44,361,151 32,827,251 251,352 3,353 5.76 10.21 2.55 0–70.20
15 469 36,118,246 26,727,502 251,574 2,689 4.80 10.06 2.32 0–69.16
20 358 29,902,138 22,127,582 250,956 2,276 4.48 10.29 1.75 0–58.53
30
 235
 23,115,711
 17,105,626
 244,380
 1,612
 2.88
9.43
 1.27
 0–58.53
District–district 2 92 29,251,073 21,645,794 244,595 3,103 12.00 14.33 6.05 0–61.19
4 68 21,069,851 15,591,689 244,595 2,343 13.60 15.03 5.35 0–61.19
7 44 14,075,282 10,415,708 252,666 1,483 17.44 14.24 7.93 0–46.79
10 18 6,021,142 4,455,645 252,049 652 18.40 14.64 9.74 0–35.28
15 18 6,021,142 4,455,645 252,049 652 18.40 15.64 9.74 0–35.28

*Weekly incidence rate thresholds were selected on the basis of best performance (sensitivity and specificity) to identify years of high annual incidence (2,534 health area years). The 3 regions had 7.5 million inhabitants.

Main Article

Page created: July 14, 2015
Page updated: July 14, 2015
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