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Volume 21, Number 8—August 2015
Research

Prevalence of Hepatitis E Virus Infection in Pigs at the Time of Slaughter, United Kingdom, 2013

Sylvia Grierson, Judith Heaney, Tanya Cheney, Dilys Morgan, Stephen Wyllie, Laura Powell, Donald Smith, Samreen Ijaz, Falko Steinbach, Bhudipa Choudhury, and Richard S. TedderComments to Author 
Author affiliations: Animal and Plant Health Agency, Addlestone, United Kingdom (S. Grierson, T. Cheney, S. Wyllie, L. Powell, F. Steinbach, B. Choudhury); Public Health England, London, United Kingdom (J. Heaney, D. Morgan, S. Ijaz, R.S. Tedder); University of Edinburgh, Edinburgh, Scotland, United Kingdom (D. Smith); University of Surrey, Guildford, United Kingdom (F. Steinbach); University College London, London (R. S. Tedder)

Main Article

Table 1

Serologic analysis of and viral RNA in cecal and plasma samples in 6 pigs ranked by viremia whose HEV plasma load at slaughter exceeded 102 IU/mL, United Kingdom*

Pig viral RNA
Serologic result†
Cecal Ct‡
 Plasma Ct
 Viremia, IU/mL§
 Wantai BR
 IgG BR
 IgM, AU/mL
 Interpretation
24.23 23.7 5.95 × 105 161 11.9 80.76 Current acute
24.71 25.5 1.92 × 105 1.03 (0.7) (2.91) Early acute
33.04 34.7 4.40 × 103 198 10.3 41.71 Current acute
37.46 34.2 2.80 × 103 299 11.6 8.94 Late acute
Not detected 34.3 570 86 11.3 4.41 Late acute
39.34 37.3 270 85 7.5 4.73 Late acute

*AU, absorbance units; BR, binding ratio test/cutoff; Ct, cycle threshold; HEV, hepatitis E virus.
†Parentheses indicate BRs below cutoff.
‡Ct for amplification trace.
§Interpolated IU/mL.

Main Article

Page created: July 14, 2015
Page updated: July 14, 2015
Page reviewed: July 14, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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