Volume 22, Number 2—February 2016
CME ACTIVITY - Research
Sustained Transmission of Pertussis in Vaccinated, 1–5-Year-Old Children in a Preschool, Florida, USA
James Matthias
, P. Scott Pritchard, Stacey W. Martin, Cristina Dusek, Erika Cathey, Rebecca D’Alessio, and Marjorie Kirsch
, P. Scott Pritchard, Stacey W. Martin, Cristina Dusek, Erika Cathey, Rebecca D’Alessio, and Marjorie Kirsch
Table
Characteristics of students, staff, and household members associated with an outbreak of pertussis in a preschool, Florida, USA*
| Characteristic | Case classification status |
Characteristic comparisons |
||||
|---|---|---|---|---|---|---|
| Confirmed | Probable | Noncase | % Cases, n = 39 | Attack rate, % | ||
| Link to preschool | ||||||
| Student | 4 | 22 | 91 | 67 | 22 | |
| Staff | 2 | 0 | 26 | 5 | 7 | |
| Household/other† | 5 | 6 | ND | 28 | ND | |
| Hospitalized |
2 |
2 |
ND |
10 |
ND |
|
| Symptoms | ||||||
| Apnea | 2 | 2 | ND | 10 | ND | |
| Cough >2 wk | 11 | 28 | ND | 100 | ND | |
| Inspiratory whoop | 5 | 2 | ND | 18 | ND | |
| Paroxysmal cough | 9 | 13 | ND | 56 | ND | |
| Posttussive vomiting |
4 |
4 |
ND |
21 |
ND |
|
| Age‡ | ||||||
| <18 mo | 1 | 1 | 7 | 8 | 22 | |
| 18 mo–4 y | 2 | 13 | 41 | 58 | 27 | |
| ≥4 y |
1 |
8 |
43 |
35 |
17 |
|
| Up-to-date pertussis vaccinations‡ | 3 | 21 | 88 | 92 | 21 | |
| No. pertussis vaccinations‡ | ||||||
| <3 | 1 | 1 | 3 | 8 | 40 | |
| 3 | 0 | 1 | 4 | 4 | 20 | |
| >4 |
3 |
20 |
81 |
88 |
22 |
|
| Time from vaccination to symptom onset, yठ| ||||||
| <1 | 1 | 6 | 39 | 27 | 15 | |
| 1–<2 | 1 | 7 | 22 | 31 | 27 | |
| 2–3 | 1 | 5 | 13 | 23 | 32 | |
| >3 |
1 |
4 |
14 |
19 |
26 |
|
| Classroom‡ | ||||||
| 1A | 1 | 1 | 11 | 8 | 15 | |
| 2A | 0 | 1 | 11 | 4 | 8 | |
| 2B | 0 | 3 | 10 | 12 | 23 | |
| 3A | 0 | 5 | 12 | 19 | 29 | |
| 3B | 2 | 6 | 9 | 31 | 47 | |
| 4A | 1 | 1 | 7 | 8 | 22 | |
| 4B | 0 | 1 | 9 | 4 | 10 | |
| 4C | 0 | 2 | 7 | 8 | 22 | |
| 4D | 0 | 2 | 6 | 8 | 25 | |
| Kindergarten | 0 | 0 | 9 | 0 | 0 | |
*ND, not determined.
†Other, symptomatic camp counselors unaffiliated with the preschool who had contact with children or siblings that attended the preschool.
‡Values and calculations are only for students in the preschool.
§For noncases, time from vaccination to symptom onset used January 1, 2014, as onset date.
Page created: January 13, 2016
Page updated: January 13, 2016
Page reviewed: January 13, 2016
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