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Volume 22, Number 6—June 2016
Synopsis

Integration of Genomic and Other Epidemiologic Data to Investigate and Control a Cross-Institutional Outbreak of Streptococcus pyogenes

Victoria J. Chalker, Alyson Smith, Ali Al-Shahib, Stella Botchway, Emily Macdonald, Roger Daniel, Sarah Phillips, Steven Platt, Michel Doumith, Rediat Tewolde, Juliana Coelho, Keith A. Jolley, Anthony Underwood, and Noel McCarthyComments to Author 
Author affiliations: Public Health England, Colindale, UK (V.J. Chalker, A. Al-Shahib, R. Daniel, S. Phillips, S. Platt, M. Doumith, R. Tewolde, J. Coelho, A. Underwood); South East England Public Health England Centre, Chilton, UK (A. Smith, S. Botchway, E. Macdonald, N.D. McCarthy); University of Oxford Department of Zoology, Oxford, UK (K.A. Jolley, N.D. McCarthy); University of Warwick, Warwick Medical School, Coventry, UK (N.D. McCarthy)

Main Article

Table

Clinical and demographic characteristics of patients with isolates sequenced in a study integrating genomic and other epidemiologic data to investigate and control a cross-institutional outbreak of Streptococcus pyogenes*

Area, laboratory no. Healthcare setting Age/sex Source of isolate Clinical presentation Outcome
1
H131441217 Care home 95 y/F Blood culture Bilateral periorbital cellulitis, sepsis Died
H131520646 Care home 91 y/M Blood culture Facial cellulitis Died, ANP
H131640460 Care home 65 y/M Nasal swab sample Rash, fever Recovered
H131620455 Care home 84 y/F Arm wound swab sample Arm cellulitis Recovered
H131720333 Care home 101 y/F Ear swab sample Weeping ear Recovered
H132060515
 Care home (CW)
 19 y/F
 Throat swab sample
 Sore throat
 Recovered
2
H131280521 Care home 94 y/F Blood culture Severe soft tissue infection Died
H131100707 Care home 84 y/F Blood culture Fever, leg cellulitis, diarrhea, vomiting NR
H131220725 Care home 93 y/F Blood culture Fever, severe cellulitis Died
H131620436 Care home 78 y/F Blood culture Emergency room admission NR
H131020872
 Maternity service
 7 d/F
 Umbilical wound swab sample
 NR
 NR
3
H131180727 Hospital 87 y/M Blood culture NR NR
H130500483
 Hospital
 60 y/M
 Blood culture
 Rash, sepsis, suspected CAP
 NR
4
H130620575 Hospital 39 y/M Pus swab sample NR NR
H130620574 Hospital 71 y/M Cannula site swab sample NR NR

*ANP, acute necrotizing pneumonitis diagnosed postmortem; CAP, community-acquired pneumonia; CW, care worker, NR not recorded.

Main Article

CrossRef reports the first author should be "High" not "Jordan" in reference 12 "Jordan, Richards, Burton, Thigpen, Van Beneden, 2007".

Reference has only first page number. Please provide the last page number if article is longer than one page. (in reference 30 "Jolley, Maiden, 2010").

CrossRef reports the year should be "2014" not "2015" in reference 37 "Davies, Holden, Coupland, Chen, Venturini, Barnett, et al., 2015".

Reference has only first page number. Please provide the last page number if article is longer than one page. (in reference 40 "Milne, Lamagni, Efstratiou, Foley, Gilman, Lilley, et al., 2011").

Page created: May 16, 2016
Page updated: May 16, 2016
Page reviewed: May 16, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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