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Volume 22, Number 9—September 2016
Letter

Specificity of Dengue NS1 Antigen in Differential Diagnosis of Dengue and Zika Virus Infection

Séverine MatheusComments to Author , Rachida Boukhari, Bhety Labeau, Valérie Ernault, Laetitia Bremand, Mirdad Kazanji, and Dominique Rousset
Author affiliations: Institut Pasteur de la Guyane, Cayenne, French Guiana (S. Matheus, B. Labeau, L. Bremand, M. Kazanji, D. Rousset); Centre Hospitalier de l’Ouest-Guyanais, Saint-Laurent du Maroni, French Guiana (R. Boukhari, V. Ernault)

Main Article

Table

RT-PCR results for 65 persons with clinical samples tested during the acute phase of Zika virus infection, French Guiana, December 17, 2015–March 2, 2016*

Days from symptom onset to sample collection No. cases RT-PCR results, by clinical sample
Serum only
 Urine only
 Serum and urine
No. samples Ct, mean ± SD No. samples Ct, mean ± SD No. samples Ct, mean ± SD
0
 8
 5
 31.8 ± 2.8
1
 34.6†
2
 Serum: 28.6 ± 10.45; urine: 28.9 ± 11.3
1
 12
 4
 29.9 ± 4.6
2
 36.5 ± 0.3
6
 Serum: 36.0 ± 1.7; urine: 33.6 ± 4.4
2
 20
 13
 32.8 ± 3.0
1
 33.7†
6
 Serum: 34.2 ± 3.6; urine: 33.0 ± 1.4
3
 15
 8
 33.6 ± 3.6
2
 34.2 ± 1.5
5
 Serum:33.6 ± 2.8; urine: 34.1 ± 1.6
4
 7
 5
 31.7 ± 2.4
1
 28.9†
1
 Serum:32†; urine: 32†
5
 3
 0
 NA
1
 31.7†
2
 Serum: 35.1 ± 0.8; urine: 32.9 ± 3.9
Total 65 35 32.5 ± 3.1 8 33.8 ± 2.6 22 Serum: 33.6 ± 3.8; urine: 32.9 ± 3.8

*Ct, cycle threshold; NA, not applicable; RT-PCR, reverse transcription PCR.
†SD not determined.

Main Article

Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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