Volume 23, Number 8—August 2017
Research Letter
Scrub Typhus as a Cause of Acute Encephalitis Syndrome, Gorakhpur, Uttar Pradesh, India
Mahima Mittal, Jeromie Wesley Vivian Thangaraj, Winsley Rose, Valsan Philip Verghese, C.P. Girish Kumar, Mahim Mittal, R. Sabarinathan, Vijay Bondre, Nivedita Gupta, and Manoj V. Murhekar
Table
Characteristics of patients with scrub typhus and controls in study of acute encephalitis syndrome, Gorakhpur, Uttar Pradesh, India, 2016
| Characteristic | No. (%) patients | No. (%) controls | Odds ratio (95% CI) | p value | Adjusted odds ratio (95% CI) |
|---|---|---|---|---|---|
| Age group,y | |||||
| <5 | 24 (52.2) | 53 (35.1) | 2.0 (0.8–5.2) | 0.152 | 7.4 (1.8–31.0) |
| 6–10 | 15 (32.6) | 67 (44.4) | 1.0 (0.4–2.7) | 0.987 | 1.8 (0.5–6.8) |
| 11–15 |
7 (15.2) |
31 (20.5) |
1 |
1 |
|
| Sex | |||||
| M | 28 (60.9) | 82 (54.3) | 1.3 (0.7–2.6) | 0.433 | |
| F |
18 (39.1) |
69 (45.7) |
1 |
||
| Orientia tsutsugamushi IgM | |||||
| Positive | 29 (63.0) | 7 (4.6) | 35.1 (13.4–92.3) | 0.000 | 29.9 (9.6–92.9) |
| Negative |
17 (37.0) |
144 (95.4) |
1 |
1 |
|
| O. tsutsugamushi IgG | |||||
| Positive | 38 (82.6) | 64 (42.4) | 6.5 (2.8–14.8) | 0.000 | 3.8 (1.4–10.9) |
| Negative | 8 (17.4) | 87 (57.6) | 1 | 1 | |
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