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Volume 23, Number 8—August 2017
Dispatch

Genesis of Influenza A(H5N8) Viruses

Rabeh El-Shesheny, Subrata Barman, Mohammed M. Feeroz, M. Kamrul Hasan, Lisa Jones-Engel, John Franks, Jasmine Turner, Patrick Seiler, David Walker, Kimberly Friedman, Lisa Kercher, Sajeda Begum, Sharmin Akhtar, Ashis Kumar Datta, Scott Krauss, Ghazi Kayali, Pamela McKenzie, Richard Webby, and Robert G. WebsterComments to Author 
Author affiliations: National Research Centre, Giza, Egypt (R. El-Shesheny); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R. El-Shesheny, S. Barman, J. Franks, J. Turner, P. Seiler, D. Walker, K. Friedman, L. Kercher, S. Krauss, P. McKenzie, R.J. Webby, R.G. Webster); Jahangirnagar University, Savar, Dhaka, Bangladesh (M.M. Feeroz, M.K. Hasan, S. Begum, S. Akhtar, A.K. Datta); University of Washington, Seattle, Washington, USA (L. Jones-Engel); University of Texas Health Sciences Center, Houston, Texas, USA (G. Kayali); Human Link, Hazmieh, Lebanon (G. Kayali)

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Figure 1

Global movement of wild birds (adapted from [8]) and geographic distribution of novel HPAI A(H5N8) viruses, 2016. Influenza A viruses were isolated from wild birds and free-ranging domestic ducks in the Tanguar haor region of Bangladesh (yellow square) during February 2015–February 2016. Dissemination of novel HPAI A(H5N8) clade 2.3.4.4 viruses (red arrows). Dashed circles indicate location of reassortment between HPAI A(H5N8) group B viruses and low pathogenicity avian influenza viruses circula

Figure 1. Global movement of wild birds (adapted from [8]) and geographic distribution of novel HPAI A(H5N8) viruses, 2016. Influenza A viruses were isolated from wild birds and free-ranging domestic ducks in the Tanguar haor region of Bangladesh (yellow square) during February 2015–February 2016. Dissemination of novel HPAI A(H5N8) clade 2.3.4.4 viruses (red arrows). Dashed circles indicate location of reassortment between HPAI A(H5N8) group B viruses and low pathogenicity avian influenza viruses circulating along the Central Asian flyway. HPAI, highly pathogenic avian influenza.

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References
  1. Lee  YJ, Kang  HM, Lee  EK, Song  BM, Jeong  J, Kwon  YK, et al. Novel reassortant influenza A(H5N8) viruses, South Korea, 2014. Emerg Infect Dis. 2014;20:1087–9. DOIPubMedGoogle Scholar
  2. Lee  DH, Torchetti  MK, Winker  K, Ip  HS, Song  CS, Swayne  DE. Intercontinental spread of Asian-origin H5N8 to North America through Beringia by migratory birds. J Virol. 2015;89:6521–4. DOIPubMedGoogle Scholar
  3. Lee  DH, Bahl  J, Torchetti  MK, Killian  ML, Ip  HS, DeLiberto  TJ, et al. Highly pathogenic avian influenza viruses and generation of novel reassortants, United States, 2014–2015. Emerg Infect Dis. 2016;22:1283–5. DOIPubMedGoogle Scholar
  4. Hill  SC, Lee  YJ, Song  BM, Kang  HM, Lee  EK, Hanna  A, et al. Wild waterfowl migration and domestic duck density shape the epidemiology of highly pathogenic H5N8 influenza in the Republic of Korea. Infect Genet Evol. 2015;34:267–77. DOIPubMedGoogle Scholar
  5. Lee  DH, Sharshov  K, Swayne  DE, Kurskaya  O, Sobolev  I, Kabilov  M, et al. Novel reassortant clade 2.3.4.4 avian influenza A(H5N8) virus in wild aquatic birds, Russia, 2016. Emerg Infect Dis. 2017;23:359–60. DOIPubMedGoogle Scholar
  6. World Organisation for Animal Health. Update on highly pathogenic avian influenza in animals (type H5 and H7) [cited 2017 Mar 21]. http://www.oie.int/animal-health-in-the-world/update-on-avian-influenza/2017/
  7. Marinova-Petkova  A, Shanmuganatham  K, Feeroz  MM, Jones-Engel  L, Hasan  MK, Akhtar  S, et al. The continuing evolution of H5N1 and H9N2 influenza viruses in Bangladesh between 2013 and 2014. Avian Dis. 2016;60(Suppl):108–17. DOIPubMedGoogle Scholar
  8. Olsen  B, Munster  VJ, Wallensten  A, Waldenström  J, Osterhaus  ADME, Fouchier  RAM. Global patterns of influenza a virus in wild birds. Science. 2006;312:384–8. DOIPubMedGoogle Scholar
  9. Tamura  K, Stecher  G, Peterson  D, Filipski  A, Kumar  S. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013;30:2725–9. DOIPubMedGoogle Scholar
  10. Pohlmann  A, Starick  E, Harder  T, Grund  C, Höper  D, Globig  A, et al. Outbreaks among wild birds and domestic poultry caused by reassorted influenza A(H5N8) clade 2.3.4.4 viruses, Germany, 2016. Emerg Infect Dis. 2017;23:633–6. DOIPubMedGoogle Scholar
  11. Jiao  P, Tian  G, Li  Y, Deng  G, Jiang  Y, Liu  C, et al. A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol. 2008;82:1146–54. DOIPubMedGoogle Scholar
  12. Seo  SH, Hoffmann  E, Webster  RG. Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med. 2002;8:950–4. DOIPubMedGoogle Scholar
  13. Wu  H, Peng  X, Xu  L, Jin  C, Cheng  L, Lu  X, et al. Novel reassortant influenza A(H5N8) viruses in domestic ducks, eastern China. Emerg Infect Dis. 2014;20:1315–8. DOIPubMedGoogle Scholar
  14. Chen  H, Smith  GJ, Zhang  SY, Qin  K, Wang  J, Li  KS, et al. Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature. 2005;436:191–2. DOIPubMedGoogle Scholar

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