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Volume 24, Number 3—March 2018

Cache Valley Virus in Aedes japonicus japonicus Mosquitoes, Appalachian Region, United States

Fan Yang1, Kevin Chan, Paul E. Marek, Philip M. Armstrong, Pengcheng Liu, Jacob E. Bova, Joshua N. Bernick, Benjamin E. McMillan, Benjamin G. Weidlich, and Sally L. PaulsonComments to Author 
Author affiliations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA (F. Yang, K. Chan, P.E. Marek, P. Liu, J.E. Bova, J.N. Bernick, B.E. McMillan, B.G. Weidlich, S.L. Paulson); The Connecticut Agricultural Experiment Station, New Haven, Connecticut, USA (P.M. Armstrong)

Main Article

Table 2

Rates of midgut infection, dissemination, and oral transmission of Cache Valley virus by Aedes japonicus japonicus mosquitoes after a 2-week extrinsic incubation, Appalachian Region, United States, 2015*

Replicate Infectious blood meal titer, log10 PFU/mL No. tested Nondisseminated infections, % Disseminated infections, % Transmission, %
1 1.2 × 106 18 44 39 33
2 1.6 × 105 26 42 42 27
3 4.6 × 106 30 37 33 27
Total Not applicable 74 41 38 28

*Virus recovered from the midgut only was classified as a nondisseminated infection. Mosquitoes with virus-positive legs and wings were considered to have a disseminated infection. If virus was detected in salivary expectorate, it was classified as transmitting.

Main Article

1Current affiliation: California Department of Public Health, Richmond, California, USA.

Page created: February 16, 2018
Page updated: February 16, 2018
Page reviewed: February 16, 2018
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